ZO1 兔多克隆抗体

Name

ZO1 Rabbit Polyclonal Antibody

Category

Polyclonal antibody(pAb); Primary antibody

Isotype

IgG

Purification

Peptide affinity purified

Immunogen

This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to ZO1.

Gene ID

7082

SwissProt

Q07157

Synonyms

TJP1; DKFZp686M05161; MGC133289; ZO-1

Category

Cytoskeletal Signaling

Background

Tight junction protein ZO-1 is a protein that in humans is encoded by the TJP1 gene. This gene encodes a protein located on a cytoplasmic membrane surface of intercellular tight junctions. The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions. ZO1 plays a role in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells.