AURORA B RABBIT MONOCLONAL ANTIBODY

背景资料

Aurora B is part of the larger AURA family of serine/threonine kinases and is a key regulator of mitotic cell division. It is involved in regulating microtubule formation and the assembly of the mitotic spindle responsible for chromosome segragation during mitosis. AURA activity is cell cycle dependent with the greatest activity occuring during mitosis. The overexpression of AURA has been well documented in many malignant cancers including breast, ovarian, colon, prostate and neuroblastomas. Overexpression of AURA appears to override checkpoints in cell cycle progression leading to increased cell division and proliferation.

应用类型

WB | AM

免疫原

人 Aurora B (AA66-80)合成肽

来源宿主

兔

反应性

人 | 小鼠

保存建议

厂家推荐蓝冰运输。收到产品后建议保存于-20篊。