HDAC4鼠单克隆抗体

背景资料

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.

应用类型

WB、E

免疫原

P56524

来源宿主

小鼠

反应性

可识别人等种属来源样本的HDAC4蛋白。

保存建议

该抗体2-8°C可保存6个月。长期保存请分装后放于 -20°C ，避免反复冻融。