SB742457 is a highly selective 5-HT6 receptor antagonist with pKi of 9.63, exhibits >100-fold selectivity over other receptors. Phase 2.
Target
5-HT6
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IC50 Value
9.63(pKi)
Diseases and Conditions
Nervous system
体外
体内
Chemical information:
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分子量
353.44
储存条件
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3 years -20 ℃ powder
2 years -80 ℃ In solvent
分子式
C19H19N3O2S
CAS:
607742-69-8
备注
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
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溶解度
体外
Ethanol
2mg/mL(5.65mM)
DMSO
78mg/ml(220.69 mM)
Water
<1mg/ml
体内
2% DMSO, 48% PEG300, 2% Tween 80 and 48% water
* <1 mg/ml refers to the product slightly soluble or insoluble
