克唑替尼

熔点

192 °C

沸点

599.2±50.0 °C(Predicted)

密度

1.47±0.1 g/cm3(Predicted)

储存条件

room temp

溶解度

Soluble in DMSO (up to 25 mg/ml with warming) or in Ethanol (up to 25 mg/ml with warming)

形态

powder

酸度系数(pKa)

9.81±0.10(Predicted)

颜色

white to tan

稳定性

Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.

InChI

1S/C21H22Cl2FN5O/c1-12(19-16(22)2-3-17(24)20(19)23)30-18-8-13(9-27-21(18)25)14-10-28-29(11-14)15-4-6-26-7-5-15/h2-3,8-12,15,26H,4-7H2,1H3,(H2,25,27)/t12-/m1/s1

InChIKey

KTEIFNKAUNYNJU-GFCCVEGCSA-N

SMILES

C1(N)=NC=C(C2=CN(C3CCNCC3)N=C2)C=C1O[C@@H](C1=C(Cl)C=CC(F)=C1Cl)C

CAS 数据库

877399-52-5

危险性符号(GHS)

GHS07,GHS08,GHS09

警示词

Warning

危险性描述

H317-H319-H341-H400

防范说明

P201-P273-P280-P302+P352-P305+P351+P338-P308+P313

安全说明

24/25

危险品运输编号

UN 3077 9 / PGIII

WGK Germany

3

危险等级

IRRITANT

海关编码

29333990

存储类别

11 - Combustible Solids

危险性类别

Aquatic Acute 1
Eye Irrit. 2
Muta. 2
Skin Sens. 1

Limited Quantities

5.0 kg (11 lbs) (solid)

Excepted Quantities

Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)