二甲基(对称)精氨酸抗体

Dimethyl (sym) Arginine Antibody

二甲基(对称)精氨酸抗体

Catalog# 目录#：ICP0811

Product Description产品描述：

This antibody is raised from rabbits that were immunized with NG,NG′-Dimethyl-L-arginine-KLH conjugates and specifically isolated and affinity purified using the NG,NG′-Dimethyl-L-arginine antigen Agarose column. The affinity purified methyl arginine antibody is useful for detection, isolation and localization of proteins with methylated arginine (symmetric dimethylation) residues.

该抗体由免疫了N,N'-二甲基-L-精氨酸-KLH结合物的兔子产生，并使用NG,NG'-二甲基-L-精氨酸抗原琼脂糖柱进行特异性分离和亲和纯化。亲和纯化的甲基精氨酸抗体可用于检测、分离和定位含有甲基化精氨酸（对称二甲基化）残基的蛋白质。Species物种：Rabbit兔

Formulation配方：

250 µg/mL in PBS, 50% glycerol

PBS中浓度为250 µg/mL，含50%甘油

Immunogen免疫原：

NG,NG′-Dimethyl-L-arginine-KLH conjugates

NG、NG′-二甲基-L-精氨酸-KLH结合物

Purification纯化：

Antigen-specific immunoaffinity purification with NG,NG′-Dimethyl-L-arginine and absorbed with NG-mono-methyl arginine.

使用NG、NG′-二甲基-L-精氨酸进行抗原特异性免疫亲和纯化，并用N-单甲基精氨酸进行吸附。

Specificity特异性：

The antibody recognizes proteins with dimethylated arginine residues. It does not cross react with acetylated proteins or mono-methylated proteins.

该抗体识别含有二甲基化精氨酸残基的蛋白质。它不会与乙酰化蛋白质或单甲基化蛋白质发生交叉反应。

Applications应用：

ELISA (1:2000), WB (1:1000), IP (5 µg/mg protein sample), IF (5 µg/mL), IHC (5 µg/mL)

Scientific Description科学描述：

Arginine methylation is a very common post-translational modification that occurs predominantly in the nucleus. The main pool of proteins that are modified in such a way possess RNA binding properties. More broadly, arginine methylation has been implicated in a variety of cellular processes, including protein trafficking, signal transduction and transcriptional regulation.

精氨酸甲基化是一种非常常见的翻译后修饰，主要发生在细胞核中。被此类修饰的主要蛋白质群体具有RNA结合特性。更广泛地说，精氨酸甲基化与多种细胞过程有关，包括蛋白质运输、信号转导和转录调节。

Storage & Stability储存与稳定性：

Product is stable for several weeks at 4°C. For extended storage, aliquot content and store product at -20°C. Avoid cycles of freezing and thawing. Expiration date is one year from date of shipping if stored properly.

产品在4°C下可稳定保存数周。如需长期储存，请分装后将产品存放在-20°C。避免反复冻融。若储存得当，保质期为发货之日起一年。