二甲基精氨酸抗体

详细介绍

Dimethyl Arginine Antibody

二甲基精氨酸抗体

Catalog #目录编号：ICP0810

Product Description产品描述：

This antibody was raised from rabbits that were immunized with NG,NG-dimethyl arginine-KLH conjugates and specifically isolated and affinity purified using the NG,NG-dimethyl arginine antigen. The affinity purified methyl arginine antibody is useful for detection, isolation and localization of proteins with methylated arginine (asymmetric dimethylation) residues.

该抗体由免疫了N,N-二甲基精氨酸-KLH结合物的兔子产生，并使用N,N-二甲基精氨酸抗原进行特异性分离和亲和纯化。亲和纯化的甲基精氨酸抗体可用于检测、分离和定位含有甲基化精氨酸（不对称二甲基化）残基的蛋白质。

Species物种：Rabbit兔

Formulation配方：

250μg/mL antibody stored in PBS, 50% glycerol

250μg/mL抗体，储存于PBS和50%甘油中

Immunogen免疫原：

NG,NG-dimethyl arginine-KLH conjugates

N,N-二甲基精氨酸-KLH结合物

Purification纯化：

Antigen-specific immunoaffinity purification with NG,NG-dimethyl arginine and adsorbed with NG-monomethyl arginine

使用N,N-二甲基精氨酸进行抗原特异性免疫亲和纯化，并用N-单甲基精氨酸吸附

Specificity特异性：

The antibody recognizes proteins with dimethylated arginine residues.  It does not cross-react with acetylated proteins or monomethylated proteins.

该抗体识别含有二甲基化精氨酸残基的蛋白质。它不会与乙酰化蛋白质或单甲基化蛋白质发生交叉反应。

Species Tested 测试物种：

Human, mouse and pig

人类、小鼠和猪

Applications应用程序：

ELISA (1:2000); WB (1:1000); IP (5 µg/mg protein sample); IF (5 µg/mL); IHC (5 µg/mL)

ELISA (1:2000)；WB (1:1000)；IP (5 µg/mg 蛋白样本)；IF (5 µg/mL)；IHC (5 µg/mL)

Scientific Description科学描述：

Arginine methylation is a very common post-translational modification that occurs predominantly in the nucleus. The main pool of proteins that are modified possess RNA binding properties. More broadly, arginine methylation has been implicated in a variety of cellular processes, including protein trafficking, signal transduction and transcriptional regulation.

精氨酸甲基化是一种非常常见的翻译后修饰，主要发生在细胞核中。被修饰的蛋白质主要具有RNA结合特性。更广泛地说，精氨酸甲基化参与了多种细胞过程，包括蛋白质运输、信号转导和转录调节。

Storage & Stability储存与稳定性：

Product is stable for several weeks at 4°C. For extended storage, store product at –20ºC. Expiration date is one year  from date of shipping if properly stored.

产品在4°C下可稳定保存数周。如需长期保存，请将产品存放在-20°C。若储存得当，保质期为配对日期起一年。