甲基（单）精氨酸抗体

Methyl (mono) Arginine Antibody

甲基（单）精氨酸抗体

Catalog#目录号：ICP0801

Product Description产品描述：

This antibody is raised from rabbits that were immunized with NG- mono-methyl arginine-KLH conjugates and was specifically isolated and affinity purified using the monomethyl-arginine antigen. The affinity purified methyl arginine antibodies are useful for detection, isolation and localization of proteins with Nγ-methylated arginine residues.

该抗体由免疫了N-单甲基精氨酸-KLH结合物的兔子产生，并使用单甲基精氨酸抗原进行特异性分离和亲和纯化。亲和纯化的甲基精氨酸抗体可用于检测、分离和定位含有Nγ-甲基化精氨酸残基的蛋白质。

Species物种：Rabbit兔

Formulation配方：

250 μg/mL in PBS, 50% glycerol

PBS中浓度为250 μg/mL，含50%甘油

Immunogen免疫原：

NG-mono-methyl arginine-KLH conjugates

N-单甲基精氨酸-KLH偶联物

Purification纯化：

Purified by antigen-specific affinity chromatography

通过抗原特异性亲和层析纯化

Specificity特异性：

The antibody recognizes free mono-methyl arginine and proteins with methylated arginine residues. It does not cross react with either asymmetric or symmetric dimethyl arginine.

该抗体识别游离的单甲基精氨酸以及含有甲基化精氨酸残基的蛋白质。它不会与不对称或对称的二甲基精氨酸发生交叉反应。

Species Tested测试物种：

Pan-specific regardless of species.

不分物种的广谱特异性。

Applications应用程序：

ELISA (1:2000); WB (1:1000); IP (5 µg/mg protein sample); IF (5 µg/mL); IHC (5 µg/mL)

Scientific Description科学描述：

Arginine methylation is a very common post-translational modification that occurs predominantly in the nucleus. The main pool of proteins that are modified possess RNA binding properties. More broadly, arginine methylation has been implicated in a variety of cellular processes, including protein trafficking, signal transduction and transcriptional regulation.

精氨酸甲基化是一种非常常见的翻译后修饰，主要发生在细胞核中。被修饰的蛋白质主要具有RNA结合特性。更广泛地说，精氨酸甲基化参与了多种细胞过程，包括蛋白质运输、信号转导和转录调节。

Storage & Stability储存与稳定性：

Product is stable for several weeks at 4°C. For extended storage,  store product at –20ºC. Expiration date is three years from date of shipping if properly stored.

产品在4°C下可稳定保存数周。如需长期储存，请将产品存放在-20°C。若储存得当，保质期为配对之日起三年。