泼尼松龙EP杂质H

Prednisolone EP Impurity H (CAS 2427-64-7), also known as 6,7-dehydro prednisolone (Δ6-prednisolone), is a prednisolone-related substance bearing an additional double bond between C6 and C7, corresponding to 11β,17α,21-trihydroxypregna-1,4,6-triene-3,20-dione (C21H26O5, MW 358.43). As the impurity officially designated Impurity H in the European Pharmacopoeia monograph for prednisolone, it is used as a reference standard for the identification and quantitation of this related substance in prednisolone APIs and finished formulations, supporting HPLC impurity profiling, method validation, and regulatory quality control.