利多卡因EP杂质G

Lidocaine EP Impurity G (CAS 42459-30-3), chemically N-(2,6-dimethylphenyl)-2-(propan-2-ylamino)acetamide (C13H20N2O, MW 220.31), is a lidocaine-related substance in which the N,N-diethylamino moiety of lidocaine is replaced by a single N-isopropyl group. As the impurity officially designated Impurity G in the European Pharmacopoeia (EP) monograph for lidocaine, it is used as a reference standard for the identification and quantification of this related substance in lidocaine APIs and pharmaceutical formulations, supporting impurity profiling, method validation, and regulatory quality control.