Mezigdomide

Mezigdomide (CC-92480) is a cereblon (CRBN) E3 ubiquitin ligase modulating agent (CELMoD) and molecular glue degrader. It binds to cereblon and modulates CRBN-mediated protein degradation, making it a useful research compound for investigating targeted protein degradation (TPD), molecular glue mechanisms, and cereblon biology . Mezigdomide has demonstrated potent antimyeloma activity and is widely used in research related to multiple myeloma and CRBN-mediated protein degradation.

• CAS No.: 2259648-80-9

• Formula: C₃₂H₃₀FN₅O₄

• Molecular Weight: 567.61 g/mol

Category: Targeted Protein Degradation (TPD) → Molecular Glues / CELMoDs → Cereblon Modulators

For research use only. Not for human or clinical use.