CC-885-CH2-PEG1-NH-CH3

CC-885-CH₂-PEG1-NH-CH₃ (CAS No. 2722698-03-3) is a functionalized derivative of CC-885 containing a short PEG1-based linker and a terminal methylamine functionality. CC-885 is a cereblon (CRBN)-recruiting compound associated with targeted protein degradation through the ubiquitin-proteasome system.

CC-885-CH₂-PEG1-NH-CH₃ can be used as a neoDegrader-related building block for the development of Antibody neoDegrader Conjugates (AnDCs) and other targeted protein degradation systems. The CC-885-derived moiety can contribute E3 ubiquitin ligase recruitment, while the linker functionality provides a site for further chemical conjugation and molecular design.

By combining an E3 ligase-recruiting component with a conjugatable linker, CC-885-CH₂-PEG1-NH-CH₃ may be useful in research involving targeted protein degradation, antibody-mediated delivery, neoDegrader development, and bioconjugation chemistry .

• CAS No.: 2722698-03-3

• Molecular Formula: C₂₆H₃₀ClN₅O₅

• Molecular Weight: 528.00 g/mol

• Applications: Targeted protein degradation, neoDegrader research, AnDC development, E3 ligase recruitment, bioconjugation, and medicinal chemistry research.

• For research use only. Not for human or clinical use.