西伦吉肽/188968-51-6；199807-35-7（TFA）/Cilengitide/cyclo(RGDf-N(Me)V-)；cyclo(arginyl-glycyl-aspartyl-D-phenylalanyl-N-methyl-valyl)

Product Name：Cilengitide

CAS No.：188968-51-6；199807-35-7（TFA）

Synonyms：西伦吉肽；cyclo(RGDf-N(Me)V-)；cyclo(arginyl-glycyl-aspartyl-D-phenylalanyl-N-methyl-valyl)

Catalog No.：143P15

Brand：Typeptide Biotech（肽研生物）

Description：Cilengitide是一条含有 RGD 序列的环肽。该肽基于体内 αv β3整合素配体，通过综合运用 环化、空间筛选和甲基化扫描而得，对αvβ3整合素具有高亲和性和选择性。试验表明，该肽不仅能较好抑制黑色素瘤和胶质细胞瘤生长，而且与放射治疗配合能提高其他肿瘤如头颈鳞状细胞瘤的治愈率，具有较好的市场前景和潜力。在多肽合成中，Cilengitide是通过固相多肽合成技术与液相多肽合成技术相结合生产出来的。

Cilengitide is a cyclic peptide containing the RGD sequence. This peptide is based on the in vivo α v β 3 integrin ligand and is obtained through the comprehensive use of cyclization, spatial screening, and methylation scanning. It has high affinity and selectivity for α v β 3 integrin. Experiments have shown that this peptide not only effectively inhibits the growth of melanoma and glioma, but also, when combined with radiotherapy, can improve the cure rate of other tumors such as head and neck squamous cell carcinoma, demonstrating promising market prospects and potential. In peptide synthesis, Cilengitide is produced by combining solid-phase peptide synthesis technology with liquid-phase peptide synthesis technology.

Purity (HPLC) ≥98.0%

Single impurity≤2%

Peptide content≥75.0%

Amino Acid Composition≤±15%

Bacterial Endotoxins≤50EU/mg

Solubility：H₂O/DMSO

Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.

Storage:Cool dry place( Store at -20°C, away from the light)

Remark:For Research Use Only. Not for human use.

订购联系方式：

南京肽研生物生物科技有限公司

手机号：19961912513(微信同号)

QQ: 2178255659

邮箱：sales@typeptide.com

联系人：顾经理

申明：本产品仅供科研使用，不得用于人体。