一、产品概述
Hu FceR1a PE AER-37 是来自BD Pharmingen品牌的高品质产品，适用于科研实验领域。
更多产品描述请查看优宁维官网(https://www.univ-bio.com/fcer1aaer-37/566608.html?mk_channel=chemicalbook)
二、产品信息
| 货号 | 566607 |
| SKU货号 | 566607 |
| 品牌 | BD Pharmingen |
| 中文名称 | Hu FceR1a PE AER-37 |
| 英文名称 | Hu FceR1a PE AER-37 |
| 抗原名称 | FceR1a |
| 宿主 | Mouse IgG2b, κ |
| 免疫原 | Recombinant Extracellular Domain of FcεR1α |
| 同种型 | Mouse IgG2b, κ |
| 克隆号 | 克隆 AER-37 (also known as CRA-1, CRA1) (RUO) |
| 荧光素标记 | PE |
简单描述
The AER-37 (CRA-1) monoclonal antibody specifically recognizes FcεRIα which is also known as the high affinity immunoglobulin epsilon receptor subunit alpha (Fc-epsilon RI-alpha). FcεRIα is a type I transmembrane glycoprotein that is encoded by
FCER1A
(Fc fragment of IgE receptor Ia) which belongs to the Ig gene superfamily. FcεRIα serves as the binding subunit for the Fc region of IgE. It forms part of a heterotetrameric, high-affinity IgE Fc receptor (FceR1/FcεR1) that includes signal transducing subunits, one β-chain (FcεRIβ encoded by
MS4A2
) and two disulfide-linked γ-subunits (FcεRIγ encoded by
FCER1G
). FcεRIα is normally expressed on basophils and mast cells and can also be expressed on some monocytes, Langerhans cells, dendritic cells, and eosinophils from allergic donors. FcεRIα plays a major role in allergic responses and in the presentation of allergens to the immune system. The AER-37 antibody reportedly does not compete with IgE for FceR1 binding.
商品描述
AER-37
The AER-37 (CRA-1) monoclonal antibody specifically recognizes FcεRIα which is also known as the high affinity immunoglobulin epsilon receptor subunit alpha (Fc-epsilon RI-alpha). FcεRIα is a type I transmembrane glycoprotein that is encoded by
FCER1A
(Fc fragment of IgE receptor Ia) which belongs to the Ig gene superfamily. FcεRIα serves as the binding subunit for the Fc region of IgE. It forms part of a heterotetrameric, high-affinity IgE Fc receptor (FceR1/FcεR1) that includes signal transducing subunits, one β-chain (FcεRIβ encoded by
MS4A2
) and two disulfide-linked γ-subunits (FcεRIγ encoded by
FCER1G
). FcεRIα is normally expressed on basophils and mast cells and can also be expressed on some monocytes, Langerhans cells, dendritic cells, and eosinophils from allergic donors. FcεRIα plays a major role in allergic responses and in the presentation of allergens to the immune system. The AER-37 antibody reportedly does not compete with IgE for FceR1 binding.
产品详情
PE
R-Phycoerythrin (PE), is part of the BD family of Phycobiliprotein dyes. This fluorochrome is a multimeric fluorescent phycobiliprotein with excitation maximum (Ex Max) of 496 nm and 566 nm and an emission maximum (Em Max) at 576 nm. PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 575/26-nm bandpass filter). As PE is excited by multiple lasers, this can result in cross-laser excitation and fluorescence spillover on instruments with various combinations of Blue, Green, and Yellow-Green lasers. Please ensure that your instrument’s configurations (lasers and optical filters) are appropriate for this dye.
格式:PE
最多激发源:496 nm, 566 nm
最多发射源:576 nm
三、背景
| 别名 | FCE1A; FCER1A; Fc-epsilon RI-alpha; FcERI; FceR1a; FcεRI |
四、制备和贮存
| 保存方式 | Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide. |
| 存储溶液 | Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide. |
五、应用
| 反应种属 | Human (QC Testing) |
| 实验应用 | Flow cytometry (Routinely Tested) |
| 目标/特异性 | Fcε Receptor Iα (FCER1A) |
六、产品特点
- 品质保证：经过严格的质量控制，确保产品的高品质和稳定性。
七、注意事项
- 本产品仅供科学研究使用，不可用于临床诊断或治疗。
- 请在通风良好的环境下操作，佩戴适当的个人防护装备。
- 如不慎接触皮肤或眼睛，请立即用大量清水冲洗并就医。
