一、产品概述
Hu CD201 BV421 RCR-252 是来自BD Pharmingen品牌的高品质产品，适用于科研实验领域。
更多产品描述请查看优宁维官网(https://www.univ-bio.com/procr/743552.html?mk_channel=chemicalbook)
二、产品信息
| 货号 | 743552 |
| SKU货号 | 743552 |
| 品牌 | BD Pharmingen |
| 英文名称 | Hu CD201 BV421 RCR-252 |
| 抗原名称 | CD201 |
| 宿主 | Rat WI, also known as Wistar (outbred) IgG1, κ |
| 免疫原 | EPCR-positive RE-1 Cells |
| 同种型 | Rat WI, also known as Wistar (outbred) IgG1, κ |
| 克隆号 | 克隆 RCR-252 (RUO) |
| 荧光素标记 | BV421 |
简单描述
The RCR-252 monoclonal antibody specifically binds to the endothelial cell protein C receptor (EPCR), which is also known as CD201. CD201 is a 25 kDa, type I transmembrane glycoprotein, expressed on endothelial cells in arteries, veins and capillaries. CD201 binds activated protein C, a serine protease that is involved in regulating blood coagulation. EPCR is reportedly expressed on several malignant cell lines. Malignant cell lines that express EPCR can show significant levels of protein C activation and this activation can be inhibited by anti-EPCR antibody
The antibody was conjugated to BD Horizon™ BV421 which is part of the BD Horizon Brilliant™ Violet family of dyes. With an Ex Max of 407-nm and Em Max at 421-nm, BD Horizon BV421 can be excited by the violet laser and detected in the standard Pacific Blue™ filter set (eg, 450/50-nm filter). BD Horizon BV421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue conjugates.
商品描述
RCR-252
The RCR-252 monoclonal antibody specifically binds to the endothelial cell protein C receptor (EPCR), which is also known as CD201. CD201 is a 25 kDa, type I transmembrane glycoprotein, expressed on endothelial cells in arteries, veins and capillaries. CD201 binds activated protein C, a serine protease that is involved in regulating blood coagulation. EPCR is reportedly expressed on several malignant cell lines. Malignant cell lines that express EPCR can show significant levels of protein C activation and this activation can be inhibited by anti-EPCR antibody
The antibody was conjugated to BD Horizon™ BV421 which is part of the BD Horizon Brilliant™ Violet family of dyes. With an Ex Max of 407-nm and Em Max at 421-nm, BD Horizon BV421 can be excited by the violet laser and detected in the standard Pacific Blue™ filter set (eg, 450/50-nm filter). BD Horizon BV421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue conjugates.
产品详情
BV421
The BD Horizon Brilliant Violet™ 421 (BV421) Dye is part of the BD Horizon Brilliant Violet™ family of dyes. This polymer-technology based dye has an excitation maximum (Ex Max) of 407-nm and an emission maximum (Em Max) at 423-nm. Driven by BD innovation, BV421 is designed to be excited by the violet laser (405-nm) and detected using an optical filter centered near 420-nm (e.g., a 431/28-nm or 450/50-nm bandpass filter). BV421 is an ideal alternative for V450 as it is approximately ten times brighter with less spillover into the BV510/V500 detector. Please ensure that your instrument’s configurations (lasers and optical filters) are appropriate for this dye.
三、背景
| 别名 | EPCR; Activated protein C receptor; APC receptor; PROCR; centrocyclin |
四、制备和贮存
| 保存方式 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
五、应用
| 反应种属 | Human (Tested in Development) |
| 实验应用 | Flow cytometry (Qualified) |
| 目标/特异性 | CD201 |
六、产品特点
- 品质保证：经过严格的质量控制，确保产品的高品质和稳定性。
七、注意事项
- 本产品仅供科学研究使用，不可用于临床诊断或治疗。
- 请在通风良好的环境下操作，佩戴适当的个人防护装备。
- 如不慎接触皮肤或眼睛，请立即用大量清水冲洗并就医。
