奥格列龙

中文名称奥格列龙中文同义词化合物T11408;(1R,2R)-1-(5-((S)-2,2-二甲基四氢-2H-吡喃-4-基)-2-(3-(4-氟-1-甲基-2,3-二氢-1H-吲唑-5-基)-2-氧代-2,3-二氢-1H-咪唑-1-基)-2-(4-氟-3,5-二甲基苯基)-4,5,6,7-四氢-2H-吡唑并[4,3-C]吡啶-5-羰基)-1;3-[(1S,2S)-1-[2-[[(4S)-2-(4-氟-3,5-二甲基苯基)-3-[3-(4-氟-1-甲基-1H-吲唑-5-基)-2,3-二氢-2-氧代-1H-咪唑-1-基]-2,4,6,7-四氢-4-甲基-5H-吡唑并[4,3-C]吡啶-5-基]羰基]-5-[(4S)-四氢-2,2-二甲基-2H-吡喃-4-基]-1H-吲唑-1-基]-2-甲基环丙基]-1,2,4-恶二唑-5(2H)-酮;GLP-1受体激动剂1;奥格列隆;3-[(1S,2S)-1-[2-[[(4S)-2-(4-氟-3,5-二甲基苯基)-3-[3-(4-氟-1-甲基-1H-吲唑-5-基)-2,3-二氢-2-氧代-1H-咪唑-1-基]-2,4,6,7-四氢-4-甲基-5H-吡唑并[4,3-C]吡啶-5-基]羰基]-5-[(4S)-四氢-2,2-二甲基-2H-吡喃-4-基]-;奥格列龙/奥氟立普龙/ORFORGLIPRON(LY-3502970);3-((1S,2S)-1-(5-((S)-2,2-二甲基四氢-2H-吡喃-4-基)-2-((S)-3-(3-(4-氟-1-甲基-1H-吲唑-5-基)-2-氧代-2,3-二氢-1H-咪唑-1-基)-2-(4-氟-3,5-二甲基苯基)-4-甲基-4,5,6,7-四氢-2H-吡唑并[4,3-C]吡啶-5-羰基)-1H-吲哚-1-基)-2-甲基环丙基)-1,2,4-噁二唑-5(4H)-酮英文名称Orforglipron英文同义词1,2,4-Oxadiazol-5(2H)-one,3-[(1S,2S)-1-[2-[[(4S)-2-(4-fluoro-3,5-dimethylphenyl)-3-[3-(4-fluoro-1-methyl-1H-indazol-5-yl)-2,3-dihydro-2-oxo-1H-imidazol-1-yl]-2,4,6,7-tetrahydro-4-methyl-5H-pyrazolo[4,3-c]pyridin-5-yl]carbonyl]-5-[(4S)-tetrahydro-2,2-dimethyl-2H-pyran-4-yl]-1H-indol-1-yl]-2-methylcy...;LY3502970;GLP-1receptoragonist1USP/EP/BP;Orforglipron;Orforglipron（LY3502970）;LY3502970(Orforglipron);3-((1S,2S)-1-(5-((S)-2,2-dimethyltetrahydro-2H-pyran-4-yl)-2-((S)-3-(3-(4-fluoro-1-methyl-1H-indazol-5-yl)-2-oxo-2,3-dihydro-1H-imidazol-1-yl)-2-(4-fluoro-3,5-dimethylphenyl)-4-methyl-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridine-5-carbonyl)-1H-indol-1-yl)-2-methylcyclopropyl)-1,2,4-oxadiazol-5(4H)-one;OWL833CAS号2212020-52-3分子式C48H48F2N10O5分子量882.97

奥格列龙性质密度1.50±0.1g/cm3(Predicted)储存条件Storeat-20°C溶解度二甲基亚砜：125mg/mL（141.57mM）形态固体酸度系数(pKa)7.33±0.20(Predicted)颜色米白色至浅黄色