PROTAC EGFR degrader 8 (T-184)

PROTAC EGFR Degrader 8 is a small-molecule proteolysis-targeting chimera (PROTAC) designed for research involving targeted degradation of the epidermal growth factor receptor (EGFR). The compound is intended for studies of EGFR-related signaling pathways, targeted protein degradation (TPD), cancer biology, and pharmaceutical drug discovery. It is supplied as a solid and is suitable for laboratory research applications.

Product Specifications: CAS No. 2925923-46-0; molecular formula C₄₀H₄₆ClN₁₁O₅; molecular weight 796.32 g/mol; purity ≥98%. The compound is soluble in DMSO. Store at −20°C in a dry and dark place to maintain product stability. When preparing solutions, use appropriate laboratory practices and consider aliquoting to minimize repeated freeze–thaw cycles. Handle the compound in accordance with applicable laboratory safety procedures.