受体激动剂多肽Enicepatide/2869147-44-2/Enicepatide

Product Name：Enicepatide

CAS No.：2869147-44-2

Synonyms：受体激动剂多肽Enicepatide

Catalog No.：220P411

Brand：Typeptide Biotech（肽研生物）

Description：Enicepatide 是一种双重抑胃肽 (GIP) 和胰高血糖素样肽 1 (GLP-1) 受体激动剂多肽，是由39个氨基酸组成的多肽。Enicepatide 可用于抗糖尿病研究。Enicepatide (CT-388) 是一种 cAMP 信号偏向性双 GLP-1R 和 GIPR 激动肽，对 GLP-1R cAMP 的 EC50 值为 0.087 nM；GIPR cAMP 的 EC50 值为 2.47 nM。Enicepatide 可激活 cAMP 信号通路，同时在两种靶标上仅招募极少量 β-arrestin-2，且受体内化水平降低。Enicepatide 可改善血糖控制、减轻体重、抑制食欲，并改善代谢功能障碍相关脂肪性肝炎的病理状况。Enicepatide 可用于肥胖、2 型糖尿病、代谢功能障碍相关脂肪性肝炎的研究。

Enicepatide is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist peptide, composed of 39 amino acids. Enicepatide can be used in anti-diabetic research. Enicepatide (CT-388) is a cAMP signal-biased dual GLP-1R and GIPR agonist peptide, with an EC50 value of 0.087 nM for GLP-1R cAMP and 2.47 nM for GIPR cAMP. Enicepatide activates the cAMP signaling pathway while recruiting only minimal β-arrestin-2 to both targets and reducing receptor internalization levels. Enicepatide improves blood glucose control, reduces body weight, suppresses appetite, and ameliorates the pathological conditions of metabolic dysfunction-associated steatohepatitis. Enicepatide can be used in studies on obesity, type 2 diabetes, and metabolic dysfunction-associated steatohepatitis.

Purity (HPLC) ≥98.0%

Single impurity≤2%

Peptide content≥75.0%

Amino Acid Composition≤±15%

Bacterial Endotoxins≤50EU/mg

Solubility：H₂O/DMSO

Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.

Storage:Cool dry place( Store at -20°C, away from the light)

Remark:For Research Use Only. Not for human use.

订购联系方式：

南京肽研生物生物科技有限公司

手机号：19961912513(微信同号)

QQ: 2178255659

邮箱：sales@typeptide.com

联系人：顾经理

申明：本产品仅供科研使用，不得用于人体。