Recombinant Human IL-7 Protein, GMP grade, HPLC-verified, DMF Filed

Recombinant Human IL‑7 Protein, GMP grade

Cat No: GMP‑11821‑HNAE｜Official product page:        https://cn.sinobiological.com/recombinant-proteins/human-il-7-gmp-11821-hnae

Specifications

Alternate Names

Background

IL7, also known as interleukin 7, is a hematopoietic growth factor that belongs to the IL‑7/IL‑9 family. It is secreted by stromal cells in the bone marrow and thymus. IL7 stimulates the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B‑cell maturation. IL7 and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre‑pro‑B cell growth‑stimulating factor. It is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRß) during early T cell development. IL7 can be produced locally by intestinal epithelial and epithelial goblet cells and may serve as a regulatory factor for intestinal mucosal lymphocytes.