递送融合寡肽ATS-9R/2431960-42-6/ATS-9R

Product Name：ATS-9R

CAS No.：2431960-42-6

Synonyms：递送融合寡肽ATS-9R

Catalog No.：220P404

Brand：Typeptide Biotech（肽研生物）

Description：ATS-9R是靶向白色脂肪组织的非病毒基因递送融合寡肽，是由18个氨基酸组成的多肽，核心生物功能为通过特异性结合细胞表面Prohibitin 蛋白，携带 shRNA、sgRNA/Cas9 等治疗性核酸靶向递送至高表达 Prohibitin 的成熟脂肪细胞、内脏脂肪组织巨噬细胞（ATMs），实现目标基因沉默（如 TACE、CCL2、FAM83A、Fabp4），进而减轻肥胖相关炎症、改善胰岛素抵抗、缓解妊娠期糖尿病（GDM）及肥胖诱导的 2 型糖尿病，减少脂肪积累。

ATS-9R is a non-viral gene delivery fusion oligopeptide targeting white adipose tissue, an 18-amino-acid polypeptide. Its core biological function involves specific binding to cell surface Prohibitin protein, carrying therapeutic nucleic acids such as shRNA and sgRNA/Cas9, and mediating targeted delivery to Prohibitin-high mature adipocytes and visceral adipose tissue macrophages (ATMs), thereby achieving target gene silencing (e.g., TACE, CCL2, FAM83A, Fabp4). Consequently, it alleviates obesity-related inflammation, improves insulin resistance, relieves gestational diabetes mellitus (GDM) and obesity-induced type 2 diabetes, and reduces fat accumulation.

Purity (HPLC) ≥98.0%

Single impurity≤2%

Peptide content≥75.0%

Amino Acid Composition≤±15%

Bacterial Endotoxins≤50EU/mg

Solubility：H₂O/DMSO

Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.

Storage:Cool dry place( Store at -20°C, away from the light)

Remark:For Research Use Only. Not for human use.

订购联系方式：

南京肽研生物生物科技有限公司

手机号：19961912513(微信同号)

QQ: 2178255659

邮箱：sales@typeptide.com

联系人：顾经理

申明：本产品仅供科研使用，不得用于人体。