BBO-8520厂家

中文名称BBO-8520,KRASG12C抑制剂

中文同义词BBO-8520,KRASG12C抑制剂;化合物BBO-8520;BBO8520杂质1;(4S)-4-(4-((2S,5R)-4-丙烯酰基-2,5-二甲基哌嗪-1-基)-8-氟-2-(((2R,7aS)-2-氟四氢-1H-吡咯嗪-7a(5H)-基)甲氧基)-6-(三氟甲基)喹唑啉-7-基)-2-氨基-7-氟苯并[b]噻吩-3-甲腈;BBO-8520(KRASG12CON/OFF双态共价)英文名称Benzo[b]thiophene-3-carbonitrile,2-amino-4-[4-[(2S,5R)-2,5-dimethyl-4-(1-oxo-2-propen-1-yl)-1-piperazinyl]-8-fluoro-2-[[(2R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy]-6-(trifluoromethyl)-7-quinazolinyl]-7-fluoro-,(4S)

英文同义词Benzo[b]thiophene-3-carbonitrile,2-amino-4-[4-[(2S,5R)-2,5-dimethyl-4-(1-oxo-2-propen-1-yl)-1-piperazinyl]-8-fluoro-2-[[(2R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy]-6-(trifluoromethyl)-7-quinazolinyl]-7-fluoro-,(4S)-;4-((R)-4-((2S,5R)-4-acryloyl-2,5-dimethylpiperazin-1-yl)-8-fluoro-2-(((2R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl)methoxy)-6-(trifluoromethyl)quinazolin-7-yl)-2-amino-7-fluorobenzo[b]thiophene;4-((R)-4-((2S,5R)-4-acryloyl-2,5-dimethylpiperazin-1-yl)-8-fluoro-2-(((2R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl)methoxy)-6-(trifluoromethyl)quinazolin-7-yl)-2-amino-7-fluorobenzo[b]thiophene-3-carbonitrile;BBO8520Impurity1;(4S)-4-(4-((2S,5R)-4-Acryloyl-2,5-dimethylpiperazin-1-yl)-8-fluoro-2-(((2R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl)methoxy)-6-(trifluoromethyl)quinazolin-7-yl)-2-amino-7-fluorobenzo[b]thiophene-3-carbonitrile

CAS号2893809-51-1分子式C35H33F6N7O2S分子量729.74

BBO-8520, KRAS G12C 抑制剂 性质沸点855.8±75.0 °C(predicted)密度1.50±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)酸度系数(pKa)8.93±0.70(predicted)形态Solid颜色White to off-white