次野鸢尾黄素

product name: Irisflorentin

cas no.:41743-73-1

chemical name;9-Methoxy-7-(3,4,5-trimethoxyphenyl)-[1,3]dioxolo[4,5-g]chromen-8-one

molecular formula: C₂₀H₁₈O₈

molecular weight:386.35

solubility: soluble in  DMSO, Acetone

appearance: powder

purity by hplc: >98%

biological activity:Irisflorentin blocks apoptosis pathways, by exerting its effects by promoting rpn-3 expression to enhance the activity of proteasomes and down-regulating egl-1 expression;  Irisflorentin has anti-inflammatory mechanism in LPS-activated RAW 264.7 macrophages, by reducing  the transcriptional and translational levels of inducible nitric oxide synthase (iNOS) as well as the production of NO.