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网站主页 COMP, HUMAN, 重组蛋白 (HIS) COMP, Human, 重组蛋白 (His)
  • COMP, Human, 重组蛋白 (His)|TMPY-00725|TargetMol

COMP, Human, 重组蛋白 (His)|TMPY-00725|TargetMol

COMP Protein, Human, Recombinant (His)
429 5μg 起订
上海 更新日期:2026-05-09

TargetMol 中国(陶术生物)

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联系人:邵经理
电话:400-821-0310拨打
手机:15002144251 拨打
邮箱:xuexiang.shao@tsbiochem.com

产品详情:

中文名称:
COMP, Human, 重组蛋白 (His)
英文名称:
COMP Protein, Human, Recombinant (His)
品牌:
TargetMol
产地:
美国
保存条件:
Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
纯度规格:
89.60%
产品类别:
抑制剂
种属:
Human
表达系统:
HEK293 Cells
蛋白长度:
A DNA sequence encoding the human COMP (NP_000086.2) precusor (Met 1-Ala 757) was expressed with a C-terminal polyhistidine tag. Predicted N terminal: Gln 21
标签:
C-His
货号:
T011|TMPY-00725

Product Introduction

Bioactivity

名称COMP Protein, Human, Recombinant (His)
描述Cartilage Oligomeric Matrix Protein (COMP), also referred to as Thrombospondin-5, is a non-collagenous extracellular matrix (ECM) protein and belongs to the subgroup B of the thrombospondin protein family. This protein is expressed primarily in cartilage, ligament, and tendon, and binds to other ECM proteins such as collagen I, II and IX with high affinities depending on the divalent cations Zn2+ or Ni2+. COMP is a secreted glycoprotein that is important for growth plate organization and function. It is suggested to play a role in cell growth and development, and recent studies have revealed the possible mechanism that it protects cells against death by elevating members of the IAP (inhibitor of apoptosis protein) family of survival proteins. Mutations in COMP cause two skeletal dysplasias, pseudoachondroplasia (PSACH) and multiple epiphyseal dysplasia (EDM1), and up-regulated expression of COMP are observed in rheumatoid arthritis and certain carcinomas.
存储条件Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
关键字THBS-5 | THBS 5 | EPD-1 | EPD 1 | EDM-1 | EDM 1
THBS5;PSACH;MED;EPD1;EDM1;cartilage oligomeric matrix protein;TargetMol

公司简介


成立日期 (14年)
注册资本 589.8595万人民币
员工人数 100-500人
年营业额 ¥ 1亿以上
经营模式 贸易,工厂,试剂,定制,服务
主营行业 天然产物,生物化工,化学试剂,生物技术服务

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