单克隆Anti-CD4抗体-ACROBiosystems百普赛斯

PE-CY7-Labeled Monoclonal Anti-Human CD4 Antibody, Mouse IgG1 (8C3)

抗体来源（Source）

Monoclonal Anti-Human CD4 Antibody, Mouse IgG1 (8C3) is a mouse monoclonal antibody produced from hybridoma.

应用（Application）

This PE-CY7-CD4 Antibody is specifically developed for flow cytometry applications to detect the expression of CD4 on human cells. Additionally, the Human TBNK 6-color Cocktail Flow Panel kit (Cat. No. ICA-A001) is available, with the PE-CY7-CD4 Antibody being one component of the kit.

种属（Species）

Mouse

亚型（Isotype）

Mouse IgG1 | Mouse kappa

特异性（Specificity）

This product is a specific antibody specifically reacts with CD4 protein.

种属反应性（Reactivity）

Human

免疫原（Immunogen）

Purified Human CD4 Protein

偶联（Conjugate）

PE-CY7

Excitation Wavelength: 561 nm

Emission Wavelength: 780 nm

推荐稀释比（Recommended Dilution）

1:20

制剂（Formulation）

Supplied as 0.2 μm-filtered solution in PBS (pH 7.4) containing 0.03% ProClin 300 and 0.2% BSA, with trehalose as protectant.

Please contact us for customized product forms or formulations.

存储（Storage）

Please protect from light and avoid repeated freeze-thaw cycles.

This product is stable after storage at:

Store at 2-8 °C for 12 months.

运输（Shipping）

This product is supplied and shipped with blue ice, please inquire the shipping cost.

背景介绍

T细胞表面糖蛋白CD4，也称为T细胞表面抗原T4/Leu-3。CD4包含三个Ig样C2型（免疫球蛋白样）结构域和一个Ig样V型（免疫球蛋白样）结构域。CD4是MHC-II类抗原与T细胞受体相互作用的辅助蛋白，能够诱导脂筏的聚集。CD4是HIV-1进入宿主T细胞的主要受体。HIV感染会导致表达CD4受体的T细胞数量进行性减少。因此，医学专业人员会参考CD4计数来决定HIV感染者的治疗起始时机。