单克隆Anti-CD71抗体-ACROBiosystems百普赛斯

Monoclonal Anti-CD71 Antibody, Mouse IgG1 (5B5) (MALS verified)

抗体来源（Source）

Monoclonal Anti-CD71 Antibody, Mouse IgG1 (5B5) is a Mouse monoclonal antibody recombinantly expressed from HEK293 cells.

克隆号（Clone）

CD71

种属（Species）

Mouse

亚型（Isotype）

Mouse IgG1 | Mouse Kappa

偶联（Conjugate）

Unconjugated

抗体类型（Antibody Type）

Recombinant Monoclonal

免疫原（Immunogen）

Recombinant Human CD71 is expressed from human 293 cells

特异性（Specificity）

Specifically recognizes Human CD71.

应用（Application）

纯度（Purity）

95% as determined by SDS-PAGE.

90% as determined by SEC-MALS.

纯化（Purification）

Protein A purified / Protein G purified

制剂（Formulation）

Lyophilized from a 0.22 μm-filtered solution in PBS (pH 7.4), with trehalose as protectant.

Please contact us for customized product forms or formulations.

重构方法（Reconstitution）

Please refer to the Certificate of Analysis (CoA) for specific instructions.

For best performance, we strongly recommend following the reconstitution protocol provided in the CoA.

存储（Storage）

For long term storage, the product should be stored in a lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

-20°C to -70°C for 12 months in lyophilized state;

-70°C for 3 months under sterile conditions after reconstitution.

交叉验证（Cross Verification）

This product No cross-reactivity in ELISA with

Rat Transferrin R, His Tag (Cat. No. TFR-R5249).

Mouse Transferrin R, His Tag (Cat. No. TFR-M524b).

背景介绍

CD抗原 CD71 又称转铁蛋白受体蛋白 1（Transferrin receptor protein 1），简称 TfR、sTfR、p90、TfR1、Trfr，属于肽酶 M28 家族及 M28B 亚家族。CD71/TFR 含有一个 PA（蛋白酶相关）结构域。CD71/TfR1 是转铁蛋白向细胞递送铁离子所必需的蛋白。在人类白血病和淋巴瘤病例中，CD71 是一个潜在的新靶点。已有研究表明，CD71/TFRC/TfR 可与 GABARAP 及 HFE 相互作用。