抑制剂醛肽，143313-51-3，Ac-Tyr-Val-Ala-Asp-aldehyde，杭州固拓生物多肽物美价廉 新品

Product Name：Caspase-1 Inhibitor I

Synonyms：四肽白介素1β转化酶(ICE)抑制剂醛肽

CAS No.：143313-51-3

Catalog No.：GT-XL0169

Brand：Go Top peptide（杭州固拓）

Description：Caspase-1 Inhibitor I通过醛基（-CHO）与Caspase-1活性位点的半胱氨酸残基巯基（-SH）形成硫代半缩醛加合物，使酶失活，抑制IL-1β前体裂解为成熟IL-1β，从而阻断炎症反应，应用于炎症性疾病研究（如类风湿关节炎、自身免疫性疾病）、细胞凋亡等研究。

Caspase-1 Inhibitor I inactivates the enzyme by forming a thiohemiacetal adduct between the aldehyde group (-CHO) and the thiol group (-SH) of the cysteine residue at the active site of Caspase-1, thereby inhibiting the cleavage of pro-IL-1β into mature IL-1β, which blocks the inflammatory response. It is used in research on inflammatory diseases (such as rheumatoid arthritis and autoimmune diseases) and studies on cell apoptosis.

Purity (HPLC) ≥98.0%

Single impurity≤2%

Peptide content≥75.0%

Amino Acid Composition≤±15%

Bacterial Endotoxins≤50EU/mg

Solubility：H2O/DMSO

Vacuum-packedwith aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.

Storage:Cool dry place( Store at -20°C, away from the light)

Remark:For Research Use Only. Not for human use.

Sequence(1-letter code)	Ac-YVAD-CHO
Sequence(3-letter code)	Ac-Tyr-Val-Ala-Asp-CHO
Peptide Structure
Molecular Formula	C23H32N4O8
Molecular Weight	492.52

申明：产品仅供科研使用，不得用于人体。

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