抑制剂多肽Nogo-66 (1-40)/475221-20-6/Nogo-66 (1-40) 新品

Product Name：Nogo-66 (1-40)

CAS No.：475221-20-6

Synonyms：抑制剂多肽Nogo-66 (1-40)

Catalog No.：218P071

Brand：Typeptide Biotech（肽研生物）

Description：Nogo-66 (1-40)是对应于Nogo-66的残基1-40的多肽，序列中含有40个氨基酸，肽链两端均被封闭，Nogo-66是抑制轴突生长的髓鞘蛋白Nogo的结构域。作为Nogo-66受体(NgR)的竞争性拮抗剂，能阻断Nogo-66和CNS髓鞘诱导的轴突生长抑制，但在体外不降低髓鞘相关糖蛋白(MAG)对轴突生长的抑制。Nogo-66 (1-40)在体内脊髓损伤后促进半切脊髓轴突的再生和运动恢复。

Nogo-66 (1-40) is a peptide corresponding to residues 1-40 of Nogo-66, containing 40 amino acids in its sequence. Both ends of the peptide chain are blocked, and Nogo-66 is the domain of Nogo, a myelin protein that inhibits axonal growth. As a competitive antagonist of Nogo-66 receptor (NgR), it can block Nogo-66 and CNS myelin induced axonal growth inhibition, but does not reduce the inhibition of myelin associated glycoprotein (MAG) on axonal growth in vitro. Nogo-66 (1-40) promotes regeneration and motor recovery of semi cut spinal cord axons after spinal cord injury in vivo.

Purity (HPLC) ≥98.0%

Single impurity≤2%

Peptide content≥75.0%

Amino Acid Composition≤±15%

Bacterial Endotoxins≤50EU/mg

Solubility：H₂O/DMSO

Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.

Storage:Cool dry place( Store at -20°C, away from the light)

Remark:For Research Use Only. Not for human use.

订购联系方式：

南京肽研生物生物科技有限公司

手机号：19961912513(微信同号)

QQ: 2178255659

邮箱：sales@typeptide.com

联系人：顾经理

申明：本产品仅供科研使用，不得用于人体。