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网站主页 GRANZYME B/GZMB, HUMAN, 重组蛋白 (HIS) Granzyme B/GZMB, Human, 重组蛋白 (His)
  • Granzyme B/GZMB, Human, 重组蛋白 (His)|TMPY-00817|TargetMol

Granzyme B/GZMB, Human, 重组蛋白 (His)|TMPY-00817|TargetMol

Granzyme B/GZMB Protein, Human, Recombinant (His)
697 5μg 起订
上海 更新日期:2026-05-09

TargetMol 中国(陶术生物)

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电话:400-821-0310拨打
手机:15002144251 拨打
邮箱:xuexiang.shao@tsbiochem.com

产品详情:

中文名称:
Granzyme B/GZMB, Human, 重组蛋白 (His)
英文名称:
Granzyme B/GZMB Protein, Human, Recombinant (His)
品牌:
TargetMol
产地:
美国
保存条件:
Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
产品类别:
抑制剂
种属:
Human
表达系统:
HEK293 Cells
蛋白长度:
A DNA sequence encoding the proform of human Granzyme B (NP_004122.1) (Met 1-Tyr 247) was expressed with a C-terminal polyhistidine tag. Predicted N terminal: Gly 19
标签:
C-His
货号:
T011|TMPY-00817

Product Introduction

Bioactivity

名称Granzyme B/GZMB Protein, Human, Recombinant (His)
描述Granzyme B, also known as GZMB, is the most prominent member of the granzyme family of cell death-inducing serine proteases expressed in the granules of cytotoxic T lymphocytes (CTLs) and NK cells. Granzyme B enters the target cells depending on another membrane-binding granule protein, perforin, results in the activation of effector caspases and mitochondrial depolarization through caspase-dependent and -independent pathways, and consequently induces rapid cell apoptosis. Over 3 substrates of GZMB have been identified including the key substrate caspase-3, ICAD, and Bid. GZMB is suggested to protect the host by lysing cells bearing on their surface 'nonself' antigens such as bacterial and viral infected-cells and tumor cells and accordingly plays an essential role in immunosurveillance.
存储条件Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
关键字granzyme B | CTSGL-1 | CTSGL 1 | CTLA-1 | CTLA 1 | CGL 1
SECT;HLP;granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1);CTSGL1;CTLA1;CSP-B;CSPB;CGL-1;CGL1;CCPI;TargetMol

公司简介


成立日期 (14年)
注册资本 589.8595万人民币
员工人数 100-500人
年营业额 ¥ 1亿以上
经营模式 贸易,工厂,试剂,定制,服务
主营行业 天然产物,生物化工,化学试剂,生物技术服务

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