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网站主页 ALDH1A1, HUMAN, 重组蛋白 (HIS) ALDH1A1, Human, 重组蛋白 (His)
  • ALDH1A1, Human, 重组蛋白 (His)|TMPY-01583|TargetMol

ALDH1A1, Human, 重组蛋白 (His)|TMPY-01583|TargetMol

ALDH1A1 Protein, Human, Recombinant (His)
1890 20μg 起订
上海 更新日期:2026-05-09

TargetMol 中国(陶术生物)

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产品详情:

中文名称:
ALDH1A1, Human, 重组蛋白 (His)
英文名称:
ALDH1A1 Protein, Human, Recombinant (His)
品牌:
TargetMol
产地:
美国
保存条件:
Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
纯度规格:
97.60%
产品类别:
抑制剂
种属:
Human
表达系统:
E. coli
蛋白长度:
A DNA sequence encoding the human ALDH1A1 (NP_000680.2) (Ser 2-Ser 501) was expressed, with a polyhistidine tag at the N-terminus. Predicted N terminal: Met
标签:
N-His
货号:
T011|TMPY-01583

Product Introduction

Bioactivity

名称ALDH1A1 Protein, Human, Recombinant (His)
描述Aldehyde dehydrogenase 1 family, member A1 (ALDH1A1), also known as Aldehyde dehydrogenase 1 (ALDH1), or Retinaldehyde Dehydrogenase 1 (RALDH1), is an enzyme that is expressed at high levels in stem cells and that has been suggested to regulate stem cell function. The retinaldehyde dehydrogenase (RALDH) subfamily of ALDHs, composed of ALDH1A1, ALDH1A2, ALDH1A3, and ALDH8A1, regulate development by catalyzing retinoic acid biosynthesis. The ALDH1A1 protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. ALDH1A1 also belongs to the group of corneal crystallins that help maintain the transparency of the cornea. Increased ALDH1A1 activity has been found in the stem cell populations of leukemia and some solid tumors. In tumor specimens, increased ALDH1A1 immunopositivity was found not only in secretory type cancer epithelial cells but also in neuroendocrine tumor populations. ALDH1 has been identified as a reliable marker of breast cancer stem cells. ALDH1 expression in primary cancer is an independent prognostic factor in node-positive breast cancer patients. ALDH1A1 plays a key role in normal hematopoiesis, and as a TLX1 transcriptional target, ALDH1A1 may contribute to the ability of this homeoprotein to alter cell fate and induce tumor growth.
存储条件Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
关键字RALDH-1 | RALDH 1 | PUMB-1 | PUMB 1 | HEL9 | HEL-12 | HEL 9 | HEL 12 | ALDH-11 | ALDH-1 | ALDH 11 | ALDH 1
RALDH1;PUMB1;HEL-S-53e;HEL-9;HEL12;ALDH-E1;ALDH11;ALDH1;aldehyde dehydrogenase 1 family, member A1;ALDC;TargetMol

公司简介


成立日期 (14年)
注册资本 589.8595万人民币
员工人数 100-500人
年营业额 ¥ 1亿以上
经营模式 贸易,工厂,试剂,定制,服务
主营行业 天然产物,生物化工,化学试剂,生物技术服务

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