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网站主页 RON/CD136, HUMAN, 重组蛋白 (HIS) RON/CD136, Human, 重组蛋白 (His)
  • RON/CD136, Human, 重组蛋白 (His)|TMPY-02028|TargetMol

RON/CD136, Human, 重组蛋白 (His)|TMPY-02028|TargetMol

RON/CD136 Protein, Human, Recombinant (His)
6750 200μg 起订
上海 更新日期:2026-05-09

TargetMol 中国(陶术生物)

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联系人:邵经理
电话:400-821-0310拨打
手机:15002144251 拨打
邮箱:xuexiang.shao@tsbiochem.com

产品详情:

中文名称:
RON/CD136, Human, 重组蛋白 (His)
英文名称:
RON/CD136 Protein, Human, Recombinant (His)
品牌:
TargetMol
产地:
美国
保存条件:
Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
纯度规格:
96.10%
产品类别:
抑制剂
货号:
TMPY-02028

Product Introduction

Bioactivity

名称RON/CD136 Protein, Human, Recombinant (His)
描述The tyrosine kinase receptor, macrophage-stimulating 1 receptor (MST1R), a c-met-related tyrosine kinase, also known as the Ron receptor or CD136, controls cell survival and motility programs related to invasive growth. As the tyrosine kinase receptor is comprised of an extracellular domain, MST1R protein contains the ligand-binding pocket and an intracellular region where the kinase domain is located. MST1R signaling may be involved in the regulation of macrophage and T-lymphocyte activation in vivo during injury. This assessment of gene expression indicates the importance of genetic factors in contributing to lung injury and points to strategies for intervention in the progression of inflammatory diseases. It had been shown that MST1R/CD136 plays a critical role in Ni-induced lung injury in mice. The overexpression of MSP, MT-SP1, and MST1R was a strong independent indicator of both metastasis and death in human breast cancer patients and significantly increased the accuracy of an existing gene expression signature for poor prognosis. Stimulation of MST1R leads to its transphosphorylation and the ultimate activation of numerous intracellular signaling pathways, such as the classical mitogen-activated protein kinase pathway, the phosphatidylinositol (PI)3-kinase pathway, and the JNK pathway.
存储条件Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
关键字PTK-8 | PTK 8 | CD-136 | CD 136
br
RON|||PTK8|||macrophage stimulating 1 receptor|||CDw136|||CD136|TargetMol

公司简介


成立日期 (14年)
注册资本 589.8595万人民币
员工人数 100-500人
年营业额 ¥ 1亿以上
经营模式 贸易,工厂,试剂,定制,服务
主营行业 天然产物,生物化工,化学试剂,生物技术服务

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