基本信息 产品详情 公司简介 推荐产品
网站主页 WWP2, HUMAN, 重组蛋白 (HIS & GST) WWP2, Human, 重组蛋白 (His & GST)
  • WWP2, Human, 重组蛋白 (His & GST)|TMPY-02950|TargetMol

WWP2, Human, 重组蛋白 (His & GST)|TMPY-02950|TargetMol

WWP2 Protein, Human, Recombinant (His & GST)
495 5μg 起订
上海 更新日期:2026-05-09

TargetMol 中国(陶术生物)

VIP1年
联系人:邵经理
电话:400-821-0310拨打
手机:15002144251 拨打
邮箱:xuexiang.shao@tsbiochem.com

产品详情:

中文名称:
WWP2, Human, 重组蛋白 (His & GST)
英文名称:
WWP2 Protein, Human, Recombinant (His & GST)
品牌:
TargetMol
产地:
美国
保存条件:
Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
产品类别:
抑制剂
种属:
Human
表达系统:
Baculovirus Insect Cells
蛋白长度:
A DNA sequence encoding the human WWP2 (O00308) (Met1-Glu870) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus. Predicted N terminal: Met
标签:
His, GST
货号:
T011|TMPY-02950

Product Introduction

Bioactivity

名称WWP2 Protein, Human, Recombinant (His & GST)
描述WWP2 contains 1 C2 domain, 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain and 4 WW domains. It is an E3 ubiquitin-protein ligase that accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. WWP2 can be detected in heart, throughout the brain, placenta, lung, liver, muscle, kidney and pancreas. It is also expressed in spleen and peripheral blood leukocytes. WWP2 polyubiquitinates POU5F1 by 'Lys-63'-linked conjugation and promotes it to proteasomal degradation; in embryonic stem cells (ESCs) the ubiquitination is proposed to regulate POU5F1 protein level. WWP2 ubiquitinates EGR2 and promotes it to proteasomal degradation; in T-cells the ubiquitination inhibits activation-induced cell death. It also ubiquitinates SLC11A2; the ubiquitination is enhanced by presence of NDFIP1 and NDFIP2. WWP2 ubiquitinates RPB1 and promotes it to proteasomal degradation.
存储条件Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
关键字AIP-2 | AIP 2
WWp2-like;WW domain containing E3 ubiquitin protein ligase 2;AIP2;TargetMol

公司简介


成立日期 (14年)
注册资本 589.8595万人民币
员工人数 100-500人
年营业额 ¥ 1亿以上
经营模式 贸易,工厂,试剂,定制,服务
主营行业 天然产物,生物化工,化学试剂,生物技术服务

WWP2, Human, 重组蛋白 (His & GST)相关厂家报价

内容声明
拨打电话 立即询价