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  • 化合物 Cyclo-(Pro-Gly)|TN6674|TargetMol

化合物 Cyclo-(Pro-Gly)|TN6674|TargetMol

Cyclo-(Pro-Gly)
99 25mg 起订
上海 更新日期:2026-05-09

TargetMol 中国(陶术生物)

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产品详情:

中文名称:
化合物 Cyclo-(Pro-Gly)
英文名称:
Cyclo-(Pro-Gly)
CAS号:
19179-12-5
品牌:
TargetMol
产地:
美国
保存条件:
Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
纯度规格:
99.33%
产品类别:
抑制剂
货号:
TN6674

Product Introduction

Bioactivity

名称Cyclo-(Pro-Gly)
描述Cyclo-(Pro-Gly) is an alkaloid with weak antibacterial activity and antioxidant properties that can inhibit Chitinase B and scavenge free radicals. It is widely used in biochemical experiments and drug synthesis research.
体外活性METHODS AND RESULTS:In the present study, an endophytic fungus isolate FTJZZJ09, which isolated from the fresh bulbs of Fritillaria thunbergii Miq., was identified as Penicillium chrysogenum based on its morphological characters and internal transcribed spacer (ITS) sequence. After being cultured in the modified CzapeK-DoX medium (3 g/L maltose, 3 g/L peptone A, 0.1 g/L K2HPO4, 0.05 g/L KCl, 0.3 g/L NaNO3, 0.05 g/L MgSO4·7H2O, 0.001 g/L FeSO4·7H2O, pH 6.5), it can secrete antibacterial metabolites under the condition of 28 °C in a rotary shaker at 160 r/min for 7 days. Three antibacterial compounds were isolated from the ethyl acetate extract of the fermentation broth by silica gel, they were elucidated as Cyclo(Pro-Gly) , cyclo (Pro-Val) and 2-acetyl-4 (3H) quinazolinone. CONCLUSIONS: All the three compounds could inhibit the growth of Bacillus subtilis with the minimal inhibitory concentration (MIC) value of 0.8, 0.8, and 0.4 g/L respectively, while they showed no apparent effects against the growth of Gram-negative bacteria.
体内活性Cyclo-(Pro-Gly) (0.1,10 mg/kg,腹腔注射) 给大鼠,在大鼠体内似乎是一种促进记忆的物质,表明再大鼠体内存在一种新的记忆调节机制。[1]
存储条件Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
溶解度DMSO : 80 mg/mL (518.91 mM), Sonication is recommended.
10% DMSO+40% PEG300+5% Tween-80+45% Saline : 5 mg/mL (32.43 mM), Sonication is recommended.
关键字Cyclo-(Pro-Gly) | Cyclo(ProGly) | Cyclo (Pro Gly)
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相关库经典已知活性库 | 已知活性化合物库 | 抗菌活性库 | 抗感染化合物库 | 天然产物库 | 烟草单体化合物库 | 抗氧化化合物库 | 高通量筛选天然产物库 | 抗感染天然产物库
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Pyrrolopiperazine-2,5-dione|||Cyclo(Pro-Gly)|TargetMol

公司简介


成立日期 (14年)
注册资本 589.8595万人民币
员工人数 100-500人
年营业额 ¥ 1亿以上
经营模式 贸易,工厂,试剂,定制,服务
主营行业 天然产物,生物化工,化学试剂,生物技术服务

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