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网站主页 CD16A, HUMAN, 重组蛋白 (F176V, HIS) CD16a, Human, 重组蛋白 (F176V, His)
  • CD16a, Human, 重组蛋白 (F176V, His)|TMPY-01964|TargetMol

CD16a, Human, 重组蛋白 (F176V, His)|TMPY-01964|TargetMol

CD16a Protein, Human, Recombinant (F176V, His)
14200 500μg 起订
上海 更新日期:2026-05-09

TargetMol 中国(陶术生物)

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产品详情:

中文名称:
CD16a, Human, 重组蛋白 (F176V, His)
英文名称:
CD16a Protein, Human, Recombinant (F176V, His)
品牌:
TargetMol
产地:
美国
保存条件:
Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
产品类别:
抑制剂
种属:
Human
表达系统:
HEK293 Cells
蛋白长度:
A DNA sequence encoding the extracellular domain (Met1-Gln208) of human CD16a (P08637-1, with natural variant Phe 176 Val) was expressed with a C-terminal polyhistidine tag. Predicted N terminal: Gly 17
标签:
C-His
货号:
T011|TMPY-01964

Product Introduction

Bioactivity

名称CD16a Protein, Human, Recombinant (F176V, His)
描述The Fc receptor with low affinity for IgG (FCGR3, or CD16) is encoded by 2 nearly identical genes, FCGR3A and FCGR3B, resulting in tissue-specific expression of alternative membrane-anchored isoforms. FCGR3A, it is also known as CD16a, encodes a transmembrane protein expressed on activated monocytes/macrophages, natural killer (NK) cells, and a subset of T cells._x000D_ CD16a / FCGR3A is a receptor expressed on NK cells that facilitates antibody dependent cellular cytotoxicity (ADCC) by binding to the Fc portion of various antibodies. CD16a / FCGR3A also has a broader function. CD16a / FCGR3A is directly involved in the lysis of some virus-infected cells and tumor cells by NK cells, independent of antibody binding. Cross-linking of CD16a / FCGR3A on NK cells resulted in increased intracellular Ca2+ levels and a cascade of biochemical events similar to those activated by the T cell receptor. CD16a / FCGR3A on human NK cells is a lysis receptor that mediates the direct killing of some virus infected and tumor cells, independent of antibody ligation.
存储条件Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
关键字IMD-20 | IMD 20 | IGFR-3 | IGFR 3 | FCR10 | FCR 10 | FCGR-3 | FCGR 3 | FCG-3 | FCG 3 | Fc gamma RIIIa | Fc fragment of IgG, low affinity IIIa, receptor | CD-16 | CD 16
IMD20;IGFR3;FCRIIIA;FCRIII;FCR-10;FCGRIII;FCGR3;FCG3;Fc γ RIIIa;Fc gamma RIIIa;Fc fragment of IgG, low affinity IIIa, receptor (CD16a);CD16A;CD16;TargetMol

公司简介


成立日期 (14年)
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员工人数 100-500人
年营业额 ¥ 1亿以上
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