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网站主页 RANKL/TNFSF11/CD254, Human, 重组蛋白 (His) RANKL/TNFSF11/CD254, Human, 重组蛋白 (His)
  • RANKL/TNFSF11/CD254, Human, 重组蛋白 (His)|TMPH-02264|TargetMol

RANKL/TNFSF11/CD254, Human, 重组蛋白 (His)|TMPH-02264|TargetMol

RANKL/TNFSF11/CD254 Protein, Human, Recombinant (His)
￥13900 1mg 起订
上海 更新日期：2026-05-09

TargetMol 中国（陶术生物）

VIP1年
联系人：邵经理
电话：400-821-0310拨打
手机：15002144251 拨打
邮箱：xuexiang.shao@tsbiochem.com

产品详情:

中文名称：
RANKL/TNFSF11/CD254, Human, 重组蛋白 (His)
英文名称：
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (His)
品牌：
TargetMol
产地：
美国
保存条件：
Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
产品类别：
抑制剂
货号：
TMPH-02264

Product Introduction

Bioactivity

名称RANKL/TNFSF11/CD254 Protein, Human, Recombinant (His)
描述Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response. May also play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy. Induces osteoclastogenesis by activating multiple signaling pathways in osteoclast precursor cells, chief among which is induction of long lasting oscillations in the intracellular concentration of Ca (2+) resulting in the activation of NFATC1, which translocates to the nucleus and induces osteoclast-specific gene transcription to allow differentiation of osteoclasts. During osteoclast differentiation, in a TMEM64 and ATP2A2-dependent manner induces activation of CREB1 and mitochondrial ROS generation necessary for proper osteoclast generation.
存储条件Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
关键字TNFSF 11 | OPG L | ODF | CD 254
br
Tumor necrosis factor ligand superfamily member 11|||TRANCE|||TNFSF11|||TNF-related activation-induced cytokine (TRANCE)|||Receptor activator of nuclear factor kappa-B ligand (RANKL)|||RANKL|||Osteoprotegerin ligand (OPGL)|||Osteoclast differentiation factor (ODF)|||OPGL|||CD254|TargetMol

公司简介


成立日期 (14年)
注册资本 589.8595万人民币
员工人数 100-500人
年营业额 ￥ 1亿以上
经营模式 贸易,工厂,试剂,定制,服务
主营行业 天然产物,生物化工,化学试剂,生物技术服务

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