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  • MELK, Human, 重组蛋白 (His & Myc)|TMPH-01642|TargetMol

MELK, Human, 重组蛋白 (His & Myc)|TMPH-01642|TargetMol

MELK Protein, Human, Recombinant (His & Myc)
16000 1mg 起订
上海 更新日期:2026-05-09

TargetMol 中国(陶术生物)

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联系人:邵经理
电话:400-821-0310拨打
手机:15002144251 拨打
邮箱:xuexiang.shao@tsbiochem.com

产品详情:

中文名称:
MELK, Human, 重组蛋白 (His & Myc)
英文名称:
MELK Protein, Human, Recombinant (His & Myc)
品牌:
TargetMol
产地:
美国
保存条件:
Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
纯度规格:
85.00%
产品类别:
抑制剂
种属:
Human
表达系统:
E. coli
蛋白长度:
1-340 aa
标签:
N-10xHis, C-Myc
货号:
T011|TMPH-01642

Product Introduction

Bioactivity

名称MELK Protein, Human, Recombinant (His & Myc)
描述Serine/threonine-protein kinase involved in various processes such as cell cycle regulation, self-renewal of stem cells, apoptosis and splicing regulation. Has a broad substrate specificity; phosphorylates BCL2L14, CDC25B, MAP3K5/ASK1 and ZNF622. Acts as an activator of apoptosis by phosphorylating and activating MAP3K5/ASK1. Acts as a regulator of cell cycle, notably by mediating phosphorylation of CDC25B, promoting localization of CDC25B to the centrosome and the spindle poles during mitosis. Plays a key role in cell proliferation and carcinogenesis. Required for proliferation of embryonic and postnatal multipotent neural progenitors. Phosphorylates and inhibits BCL2L14, possibly leading to affect mammary carcinogenesis by mediating inhibition of the pro-apoptotic function of BCL2L14. Also involved in the inhibition of spliceosome assembly during mitosis by phosphorylating ZNF622, thereby contributing to its redirection to the nucleus. May also play a role in primitive hematopoiesis.
存储条件Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
关键字pEg3 kinase | KIAA 0175 | hPK38 | hPK 38
Tyrosine-protein kinase MELK;Protein kinase PK38 (hPK38);Protein kinase Eg3 (pEg3 kinase);MELK;Maternal embryonic leucine zipper kinase;KIAA0175;hMELK;TargetMol

公司简介


成立日期 (14年)
注册资本 589.8595万人民币
员工人数 100-500人
年营业额 ¥ 1亿以上
经营模式 贸易,工厂,试剂,定制,服务
主营行业 天然产物,生物化工,化学试剂,生物技术服务

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