APE1/APEX1, Human, 重组蛋白 (His)|TMPY-02433|TargetMol

APE1/APEX1 Protein, Human, Recombinant (His)

￥1330 20μg 起订

上海更新日期：2026-05-09

TargetMol 中国（陶术生物）

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邮箱：xuexiang.shao@tsbiochem.com

保存条件：: Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

名称	APE1/APEX1 Protein, Human, Recombinant (His)
描述	The enzyme is known to be a redox factor (Ref-1) stimulating DNA binding activity of AP-1 binding proteins such as Fos and Jun as well as a multifunctional DNA repair enzyme having 5' AP endonuclease, DNA 3' repair diesterase, 3'-5' exonuclease and DNA 3'-phosphatase activities.Although Apex mRNA was expressed ubiquitously, the levels varied significantly, suggesting organ- or tissue-specific expression of the Apex gene. The highest level was observed in the testis, relatively high levels in the thymus, spleen, kidney and brain, and the lowest level in the liver in rats. However, the present results suggested that APEX/Ref-1 gene product can interact with AP-1 binding proteins in brain, especially in the hippocampal formation, to regulate some brain functions by redox-activation.
存储条件	Store at low temperature Lyophilized powder: -20~-80°C for 1 year \| Solution: -80°C for 6 months
关键字	REF-1 \| REF 1 \| HAP-1 \| HAP 1 \| APE-1 \| APE 1

REF1|||HAP1|||APX|||APEX nuclease (multifunctional DNA repair enzyme) 1|||APEX|||APEN|||APE1|||APE|TargetMol

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