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网站主页 CD82, HUMAN, 重组蛋白 (HIS) CD82, Human, 重组蛋白 (His)
  • CD82, Human, 重组蛋白 (His)|TMPY-02030|TargetMol

CD82, Human, 重组蛋白 (His)|TMPY-02030|TargetMol

CD82 Protein, Human, Recombinant (His)
1590 20μg 起订
上海 更新日期:2026-05-09

TargetMol 中国(陶术生物)

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产品详情:

中文名称:
CD82, Human, 重组蛋白 (His)
英文名称:
CD82 Protein, Human, Recombinant (His)
品牌:
TargetMol
产地:
美国
保存条件:
Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
纯度规格:
97.60%
产品类别:
抑制剂
种属:
Human
表达系统:
HEK293 Cells
蛋白长度:
A DNA sequence encoding the second extracellular domain of human CD82 (P27701-1) (Gly 111-Leu 228) was fused with a polyhistidine tag at the C-terminus and a signal peptide at the N-terminus. Predicted N terminal: Gly 111
标签:
C-His
货号:
T011|TMPY-02030

Product Introduction

Bioactivity

名称CD82 Protein, Human, Recombinant (His)
描述CD82, also known as KAI-1, structurally belongs to tetraspanin family while categorised as metastasis suppressor gene on functional grounds. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signalling. Downregulation of CD82 expression is associated with the advanced stages of many human cancers and correlates with the acquisition of metastatic potential. Recent studies suggest that complex mechanisms underlie CD82 loss of function, including altered transcriptional regulation, splice variant production and post-translational protein modifications, and indicate a central role for CD82 in controlling metastasis as a 'molecular facilitator'. The loss of KAI1/CD82 expression in invasive and metastatic cancers is due to a complex, epigenetic mechanism that probably involves transcription factors such as NFkappaB, p53, and beta-catenin. A loss of KAI1 expression is also associated with the advanced stages of many human malignancies and results in the acquisition of invasive and metastatic capabilities by tumour cells. Thus, KAI1/CD82 is regarded as a wide-spectrum tumor metastasis suppressor.
存储条件Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
关键字TSPAN-27 | TSPAN 27 | ST-6 | ST 6 | SAR-2 | SAR 2 | R-2 | R 2 | KAI 1 | IA-4 | IA 4 | GR-15 | GR 15 | C-33 | C 33
TSPAN27;ST6;SAR2;R2;KAI-1;KAI1;IA4;GR15;CD82 molecule;C33;4F9;TargetMol

公司简介


成立日期 (14年)
注册资本 589.8595万人民币
员工人数 100-500人
年营业额 ¥ 1亿以上
经营模式 贸易,工厂,试剂,定制,服务
主营行业 天然产物,生物化工,化学试剂,生物技术服务

CD82, Human, 重组蛋白 (His)相关厂家报价

  • 重组蛋白
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  • 2026-05-21
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