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网站主页 ACID PHOSPHATASE/ACP1, HUMAN, 重组蛋白 (GST) Acid Phosphatase/ACP1, Human, 重组蛋白 (GST)
  • Acid Phosphatase/ACP1, Human, 重组蛋白 (GST)|TMPY-02131|TargetMol

Acid Phosphatase/ACP1, Human, 重组蛋白 (GST)|TMPY-02131|TargetMol

Acid Phosphatase/ACP1 Protein, Human, Recombinant (GST)
4430 100μg 起订
上海 更新日期:2026-05-09

TargetMol 中国(陶术生物)

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产品详情:

中文名称:
Acid Phosphatase/ACP1, Human, 重组蛋白 (GST)
英文名称:
Acid Phosphatase/ACP1 Protein, Human, Recombinant (GST)
品牌:
TargetMol
产地:
美国
保存条件:
Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
产品类别:
抑制剂
种属:
Human
表达系统:
E. coli
蛋白长度:
A DNA sequence encoding human ACP1 (AAI06012.1) (Met 1-His 158) was fused with the GST tag at the N-terminus. Predicted N terminal: Met
标签:
N-GST
货号:
T011|TMPY-02131

Product Introduction

Bioactivity

名称Acid Phosphatase/ACP1 Protein, Human, Recombinant (GST)
描述The low molecular weight phosphotyrosine phosphatase (LMW-PTP), also known as Acid phosphatase 1 (ACP1), belongs to the low molecular weight phosphotyrosine protein phosphatase family are involved in the regulation of important physiological functions, including stress resistance and synthesis of the polysaccharide capsule. ACP1/LMW-PTP is an enzyme involved in platelet-derived growth factor-induced mitogenesis and cytoskeleton rearrangement. LMW-PTP is able to specifically bind and dephosphorylate activated PDGF receptor, thus modulating PDGF-induced mitogenesis. In vitro, LMW-PTP was found to efficiently dephosphorylate activated FcgammaRIIA and LAT, but not Syk or phospholipase Cgamma2. The overexpression of LMW-PTP inhibited activation of Syk downstream of FcgammaRIIA and reduced intracellular Ca(2+) mobilization. It been demonstrated that LMW-PTP is responsible for FcgammaRIIA dephosphorylation, and is implicated in the down-regulation of cell activation mediated by this ITAM-bearing immunoreceptor. In addition, ACP1 is a highly polymorphic phosphatase that is especially abundant in the central nervous system and is known to be involved in several signal transduction pathways.
存储条件Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
HAAP;acid phosphatase 1, soluble;TargetMol

公司简介


成立日期 (14年)
注册资本 589.8595万人民币
员工人数 100-500人
年营业额 ¥ 1亿以上
经营模式 贸易,工厂,试剂,定制,服务
主营行业 天然产物,生物化工,化学试剂,生物技术服务

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