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网站主页 INTEGRIN ALPHA V BETA 8, HUMAN, 重组蛋白 (HIS) Integrin alpha V beta 8, Human, 重组蛋白 (His)
  • Integrin alpha V beta 8, Human, 重组蛋白 (His)|TMPY-05717|TargetMol

Integrin alpha V beta 8, Human, 重组蛋白 (His)|TMPY-05717|TargetMol

Integrin alpha V beta 8 Protein, Human, Recombinant (His)
19000 500μg 起订
上海 更新日期:2026-05-09

TargetMol 中国(陶术生物)

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联系人:邵经理
电话:400-821-0310拨打
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邮箱:xuexiang.shao@tsbiochem.com

产品详情:

中文名称:
Integrin alpha V beta 8, Human, 重组蛋白 (His)
英文名称:
Integrin alpha V beta 8 Protein, Human, Recombinant (His)
品牌:
TargetMol
产地:
美国
保存条件:
Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
产品类别:
抑制剂
种属:
Human
表达系统:
HEK293 Cells
蛋白长度:
A DNA sequence encoding the extracellular domain (Met1-Val992) of human ITGAV (P06756) was fused with a C-terminal polyhistidine tag was expressed., constructed the plasmid 1; A DNA sequence encoding the extracellular domain (Met1-Arg684) of human ITGB8 (P26012) constructed the plasmid 2. The two plasmids were co-expressed and the human ITGAV&ITGB8 heterodimer was purified. Predicted N terminal: Phe31 & Glu43
标签:
C-His
货号:
T011|TMPY-05717

Product Introduction

Bioactivity

名称Integrin alpha V beta 8 Protein, Human, Recombinant (His)
描述Integrin alpha V beta 8 is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligands. ITGAVB8 does not appear to assume different activation states; and the cytoplasmic tail does not connect to the cytoskeleton. It binds ligands containing an RGD motif; including vitronectin; fibrin and the latency associated peptide (LAP) of the latent TGF-beta complex. High affinity binding of alpha V beta 8 to LAP allows proteolytic cleavage by MT1-MMP; which releases active TGF-beta. This mechanism differs from that of alpha V beta 6; the other alpha V integrin which can activate TGF-beta from latency through non-proteolytic mechanisms.
存储条件Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
Integrin α V β 8;Integrin alpha V β8;TargetMol

公司简介


成立日期 (14年)
注册资本 589.8595万人民币
员工人数 100-500人
年营业额 ¥ 1亿以上
经营模式 贸易,工厂,试剂,定制,服务
主营行业 天然产物,生物化工,化学试剂,生物技术服务

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