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网站主页 CATHEPSIN V, HUMAN, 重组蛋白 (HIS) Cathepsin V, Human, 重组蛋白 (His)
  • Cathepsin V, Human, 重组蛋白 (His)|TMPY-01249|TargetMol

Cathepsin V, Human, 重组蛋白 (His)|TMPY-01249|TargetMol

Cathepsin V Protein, Human, Recombinant (His)
￥1930 20μg 起订
上海 更新日期：2026-05-08

TargetMol 中国（陶术生物）

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联系人：邵经理
电话：400-821-0310拨打
手机：15002144251 拨打
邮箱：xuexiang.shao@tsbiochem.com

产品详情:

中文名称：
Cathepsin V, Human, 重组蛋白 (His)
英文名称：
Cathepsin V Protein, Human, Recombinant (His)
品牌：
TargetMol
产地：
美国
保存条件：
Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
产品类别：
抑制剂
种属：
Human
表达系统：
HEK293 Cells
蛋白长度：
A DNA sequence encoding the full length of human cathepsin L2 (NP_001324.2) (Met 1-Val 334) was expressed, with a C-terminal polyhistidine tag. Predicted N terminal: Val 18
标签：
C-His
货号：
T011|TMPY-01249

Product Introduction

Bioactivity

名称Cathepsin V Protein, Human, Recombinant (His)
描述Cathepsin V (CTSV), also known as Cathepsin L2, CTSL2, and CATL2, is a member of the peptidase C1 family. It is predominantly expressed in the thymus and testis. Cathepsin V is also expressed in corneal epithelium, and to a lesser extent in conjuctival epithelium and skin. It is a lysosomal cysteine proteinase that may play an important role in corneal physiology. It has about 75% protein sequence identity to murine cathepsin L. The fold of this enzyme is similar to the fold adopted by other members of the papain superfamily of cysteine proteases. Cathepsin V has been recently described as highly homologous to Cathepsin L and exclusively expressed in human thymus and testis. Cathepsin V is the dominant cysteine protease in cortical human thymic epithelial cells, while Cathepsin L and Cathepsin S seem to be restricted to dendritic and macrophage-like cells. Active Cathepsin V in thymic lysosomal preparations was demonstrated by active-site labeling. Recombinant Cathepsin V was capable of converting Ii into CLIP efficiently, suggesting that it is the protease that controls the generation of alphabeta-CLIP complexes in the human thymus. Cathepsin V is the third elastolytic cysteine protease which exhibits the most potent elastase activity yet described among human proteases and that it is present in atherosclerotic plaque specimens. Cathepsin L2 may play a specialized role in the thymus and testis. Expression analysis of cathepsin L2 in human tumors revealed a widespread expression in colorectal and breast carcinomas but not in normal colon or mammary gland or in peritumoral tissues. Cathepsin L2 was also expressed by colorectal and breast cancer cell lines as well as by some tumors of diverse origin, including ovarian and renal carcinomas.
存储条件Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
关键字MGC-125957 | MGC 125957 | CTSL-2 | CTSL 2 | CATL-2 | CATL 2
MGC125957;CTSV;CTSU;CTSL2;CATL2;cathepsin V;TargetMol

公司简介


成立日期 (14年)
注册资本 589.8595万人民币
员工人数 100-500人
年营业额 ￥ 1亿以上
经营模式 贸易,工厂,试剂,定制,服务
主营行业 天然产物,生物化工,化学试剂,生物技术服务

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