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网站主页 NQO1, HUMAN, 重组蛋白 (HIS) NQO1, Human, 重组蛋白 (His)
  • NQO1, Human, 重组蛋白 (His)|TMPY-03407|TargetMol

NQO1, Human, 重组蛋白 (His)|TMPY-03407|TargetMol

NQO1 Protein, Human, Recombinant (His)
1150 10μg 起订
上海 更新日期:2026-05-08

TargetMol 中国(陶术生物)

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联系人:邵经理
电话:400-821-0310拨打
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邮箱:xuexiang.shao@tsbiochem.com

产品详情:

中文名称:
NQO1, Human, 重组蛋白 (His)
英文名称:
NQO1 Protein, Human, Recombinant (His)
品牌:
TargetMol
产地:
美国
保存条件:
Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
产品类别:
抑制剂
种属:
Human
表达系统:
E. coli
蛋白长度:
A DNA sequence encoding the mature form of human NQO1 (P15559-1) (Met1-Lys274) was expressed with a polyhistide tag at the N-terminus. Predicted N terminal: His
标签:
N-His
货号:
T011|TMPY-03407

Product Introduction

Bioactivity

名称NQO1 Protein, Human, Recombinant (His)
描述NQO1 gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. NQO1 forms homodimers and reduces quinones to hydroquinones. NQO1's enzymatic activity prevents the one-electron reduction of quinones that results in the production of radical species. Mutations in the NQO1 gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of NQO1 has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. Recent pharmacological research suggests the feasibility of genotype-directed redox chemotherapeutic intervention targeting NQO1 breast cancer, a common missense genotype encoding a functionally impaired NQO1 protein.
存储条件Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
关键字QR-1 | QR 1 | NMOR-1 | NMOR 1 | DIA-4 | DIA 4
QR1;NMORI;NMOR1;NAD(P)H dehydrogenase, quinone 1;DTD;DIA4;DHQU;TargetMol

公司简介


成立日期 (14年)
注册资本 589.8595万人民币
员工人数 100-500人
年营业额 ¥ 1亿以上
经营模式 贸易,工厂,试剂,定制,服务
主营行业 天然产物,生物化工,化学试剂,生物技术服务

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