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网站主页 CYSTATIN B, HUMAN, 重组蛋白 (HIS) Cystatin B, Human, 重组蛋白 (His)
  • Cystatin B, Human, 重组蛋白 (His)|TMPY-02090|TargetMol

Cystatin B, Human, 重组蛋白 (His)|TMPY-02090|TargetMol

Cystatin B Protein, Human, Recombinant (His)
￥2260 50μg 起订
上海 更新日期：2026-05-08

TargetMol 中国（陶术生物）

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产品详情:

中文名称：
Cystatin B, Human, 重组蛋白 (His)
英文名称：
Cystatin B Protein, Human, Recombinant (His)
品牌：
TargetMol
产地：
美国
保存条件：
Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
产品类别：
抑制剂
种属：
Human
表达系统：
E. coli
蛋白长度：
A DNA sequence encoding the human CSTB (P04080) (Met 2-Phe 98) was expressed, with a polyhistide tag at the N-terminus. Predicted N terminal: Met
标签：
N-His
货号：
T011|TMPY-02090

Product Introduction

Bioactivity

名称Cystatin B Protein, Human, Recombinant (His)
描述Cystatin-B, also known as CPI-B, Liver thiol proteinase inhibitor, Stefin-B, CSTB and CST6, is a cytoplasm and nucleus protein which belongs to thecystatin family. Cystatin-B / CSTB is an intracellular thiol proteinase inhibitor. Tightly binding reversible inhibitor of cathepsins L, H and B. Cystatin-B / CSTB is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. Cystatin-B / CSTB is also thought to play a role in protecting against the proteases leaking from lysosomes. Defects in Cystatin-B / CSTB are the cause of progressive myoclonic epilepsy type 1 (EPM1) which is an autosomal recessive disorder characterized by severe, stimulus-sensitive myoclonus and tonic-clonic seizures. The cystatins are a family of cysteine protease inhibitors with homology to chicken cystatin. Cystatins are physiological inhibitors of cysteine proteinases which are widely distributed in human tissues and fluids. Cystatins typically comprise about 115 amino acids, are largely acidic, contain four conserved cysteine residues known to form two disulfide bonds. Cystatins may be glycosylated and / or phosphorylated, with similarity to fetuins, kininogens, stefins, histidine-rich glycoproteins and cystatin-related proteins. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired inhibitory activity. Cystatins mainly inhibit peptidases belonging to peptidase families C1 (papain family) and C13 (legumain family).
存储条件Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
关键字stefin B | EPM-1 | EPM 1 | cystatin B | CST-6 | CST 6
ULD;STFB;PME;EPM1A;EPM1;cystatin B (stefin B);CST6;TargetMol

公司简介


成立日期 (14年)
注册资本 589.8595万人民币
员工人数 100-500人
年营业额 ￥ 1亿以上
经营模式 贸易,工厂,试剂,定制,服务
主营行业 天然产物,生物化工,化学试剂,生物技术服务

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