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网站主页 J CHAIN, HUMAN, 重组蛋白 (HIS) J chain, Human, 重组蛋白 (His)
  • J chain, Human, 重组蛋白 (His)|TMPY-01918|TargetMol

J chain, Human, 重组蛋白 (His)|TMPY-01918|TargetMol

J chain Protein, Human, Recombinant (His)
258 5μg 起订
上海 更新日期:2026-05-08

TargetMol 中国(陶术生物)

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产品详情:

中文名称:
J chain, Human, 重组蛋白 (His)
英文名称:
J chain Protein, Human, Recombinant (His)
品牌:
TargetMol
产地:
美国
保存条件:
Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
产品类别:
抑制剂
种属:
Human
表达系统:
E. coli
蛋白长度:
A DNA sequence encoding the mature form of human IGJ (NP_653247.1) (Gln 23-Asp 159) was fused with a polyhistidine tag at the C-terminus and a pelB singnal peptide at the N-terminus. Predicted N terminal: Gln 23
标签:
C-His
货号:
T011|TMPY-01918

Product Introduction

Bioactivity

名称J chain Protein, Human, Recombinant (His)
描述Immunoglobulin J chain, also known as IGJ and IGCJ, is a secreted polypeptide which is the first immunoglobulin-related polypeptide expressed during the embryogenesis and differentiation of B cells in the fetal liver. The joining Immunoglobulin J chain is a small polypeptide, expressed by mucosal and glandular plasma cells, which regulates polymer formation of immunoglobulin (Ig)A and IgM. Immunoglobulin J chain / IGJ serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA, it induces larger polymers. Immunoglobulin J chain / IGJ also helps to bind these immunoglobulins to the secretory component. J-chain incorporation into polymeric IgA (pIgA, mainly dimers) and pentameric IgM endows these antibodies with several salient features. Immunoglobulin J chain / IGJ is involved in creating the binding site for pIgR / SC in the Ig polymers, not only by determining the polymeric quaternary structure but also by interacting directly with the receptor protein. Both the immunoglobulin J chain / IGJ and the pIgR/SC are key proteins in secretory immunity.
存储条件Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
JCH;immunoglobulin joining chain;IGCJ;TargetMol

公司简介


成立日期 (14年)
注册资本 589.8595万人民币
员工人数 100-500人
年营业额 ¥ 1亿以上
经营模式 贸易,工厂,试剂,定制,服务
主营行业 天然产物,生物化工,化学试剂,生物技术服务

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