化合物 Benzocaine hydrochloride|T6782|TargetMol

Benzocaine hydrochloride

￥198 25mg 起订

￥356 50mg 起订

￥640 100mg 起订

上海更新日期：2026-05-08

TargetMol 中国（陶术生物）

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产品详情:

中文名称：: 化合物 Benzocaine hydrochloride

英文名称：: Benzocaine hydrochloride

CAS号：: 23239-88-5

品牌：: TargetMol

产地：: 美国

保存条件：: Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

产品类别：: 抑制剂

货号：: T6782

Product Introduction

Bioactivity

名称	Benzocaine hydrochloride
描述	Benzocaine hydrochloride (Ethyl 4-aminobenzoate hydrochloride) is a surface anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings.
体外活性	AZD7762, a more selective Chk1 inhibitor, inhibits Chk1 phosphorylation of a cdc25C peptide by reversibly binding to the ATP-binding site of Chk1, with IC50 of 5 nM and Ki of 3.6 nM. AZD7762 induces cell arrest with EC50 of 0.620 μM, and significantly abrogates the camptothecin induced G2 arrest with an EC50 of 10 nM, by blocking the chk1 dependent degradation of Cdc25A and activation of Cyclin A. AZD7762 (300 nM) enhances the antitumor efficacy of gemcitabine against SW620 and topotecan against MDA-MB-231 by reducing the GI50 values from 24.1 nM and 2.25 μM to 1.08 nM and 0.15 μM, respectively. [1] AZD7762 shows cytotoxicity against a variety of neuroblastoma cell lines bearing p53 wild type, p53 mutation, Mdm2 amplification or p14 deletion with IC50 values ranging from 82.6-505.9 nM. [2]
存储条件	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
溶解度	DMSO : 38 mg/mL (188.45 mM), Sonication is recommended. Ethanol : 38 mg/mL (188.45 mM), Sonication is recommended. H2O : <1 mg/mL
关键字	SodiumChannel \| Sodium Channel \| Ethyl p-aminobenzoate Hydrochloride \| Ethyl 4-aminobenzoate Hydrochloride \| Benzocaine hydrochloride
相关产品	Adipic dihydrazide \| Levulinic acid \| Doxycycline \| Neomycin sulfate \| Terbinafine hydrochloride \| BES \| Dimethyl sulfoxide \| Sodium bicarbonate \| Hyaluronic acid sodium (MW 20 kDa) \| Sodium diacetate \| Sulfamethoxazole sodium \| D(+)-Raffinose pentahydrate

Ethyl p-aminobenzoate hydrochloride|||Ethyl 4-aminobenzoate hydrochloride|||Benzocaine HCl|TargetMol

公司简介

成立日期	(14年)
注册资本	589.8595万人民币
员工人数	100-500人
年营业额	￥ 1亿以上
经营模式	贸易,工厂,试剂,定制,服务
主营行业	天然产物,生物化工,化学试剂,生物技术服务