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网站主页 GAS6, MOUSE, 重组蛋白 (HIS) GAS6, Mouse, 重组蛋白 (His)
  • GAS6, Mouse, 重组蛋白 (His)|TMPY-04830|TargetMol

GAS6, Mouse, 重组蛋白 (His)|TMPY-04830|TargetMol

GAS6 Protein, Mouse, Recombinant (His)
987 10μg 起订
上海 更新日期:2026-05-08

TargetMol 中国(陶术生物)

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联系人:邵经理
电话:400-821-0310拨打
手机:15002144251 拨打
邮箱:xuexiang.shao@tsbiochem.com

产品详情:

中文名称:
GAS6, Mouse, 重组蛋白 (His)
英文名称:
GAS6 Protein, Mouse, Recombinant (His)
品牌:
TargetMol
产地:
美国
保存条件:
Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
纯度规格:
98.00%
产品类别:
抑制剂
种属:
Mouse
表达系统:
HEK293 Cells
蛋白长度:
A DNA sequence encoding the mouse GAS6 (NP_062394.2) (Met1-Pro674) was expressed with a polyhistidine tag at the C-terminus. Predicted N terminal: Val 28
标签:
C-His
货号:
T011|TMPY-04830

Product Introduction

Bioactivity

名称GAS6 Protein, Mouse, Recombinant (His)
描述The growth arrest-specific 6 gene (GAS6) is a member of the family of plasma vitamin K-dependent proteins, which are able to bind to phospholipids using an N-terminal gamma-carboxyglutamic acid domain. GAS6 is a vitamin K-dependent protein, plays a role in the survival, proliferation, migration, differentiation, adhesion, and apoptosis of cells. The growth arrest-specific 6 (GAS6) has been implicated in systemic inflammation and coagulation. Growth arrest-specific 6 (GAS6), plays a role in tumor progression by regulating growth in many cancers. GAS6, expressed by osteoblasts in the bone marrow, plays a significant role in the regulation of PCa cell survival during chemotherapy, which will have important implications for targeting metastatic disease. The GAS6/TYRO3-AXL-MERTK (TAM) signaling pathway is essential for full and sustained platelet activation, as well as thrombus stabilization. Inhibition of this pathway decreases platelet aggregation, shape change, clot retraction, aggregate formation under flow conditions, and surface expression of activation markers. It had been show that GAS6 signaling regulates invasion, proliferation, chemotherapy-induced apoptosis of prostate cancer (PCa) cells, and GAS6 secreted from osteoblasts in the bone marrow environment plays a critical role in establishing prostate tumor cell dormancy.
存储条件Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
growth arrest-specific 6;Gas-6;TargetMol

公司简介


成立日期 (14年)
注册资本 589.8595万人民币
员工人数 100-500人
年营业额 ¥ 1亿以上
经营模式 贸易,工厂,试剂,定制,服务
主营行业 天然产物,生物化工,化学试剂,生物技术服务

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