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网站主页 MMP-12, HUMAN, 重组蛋白 (CATALYTIC DOMAIN) MMP-12, Human, 重组蛋白 (catalytic domain)
  • MMP-12, Human, 重组蛋白 (catalytic domain)|TMPY-02869|TargetMol

MMP-12, Human, 重组蛋白 (catalytic domain)|TMPY-02869|TargetMol

MMP-12 Protein, Human, Recombinant (catalytic domain)
￥687 5μg 起订
上海 更新日期：2026-05-08

TargetMol 中国（陶术生物）

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联系人：邵经理
电话：400-821-0310拨打
手机：15002144251 拨打
邮箱：xuexiang.shao@tsbiochem.com

产品详情:

中文名称：
MMP-12, Human, 重组蛋白 (catalytic domain)
英文名称：
MMP-12 Protein, Human, Recombinant (catalytic domain)
品牌：
TargetMol
产地：
美国
保存条件：
Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
纯度规格：
90.60%
产品类别：
抑制剂
种属：
Human
表达系统：
E. coli
蛋白长度：
A DNA sequence encoding human MMP12 (NP_002417.2) (Gly106-Asn268) was expressed with a N-terminal Met. Predicted N terminal: Met
标签：
Tag Free
货号：
T011|TMPY-02869

Product Introduction

Bioactivity

名称MMP-12 Protein, Human, Recombinant (catalytic domain)
描述Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, differentiation, angiogenesis, and tissue remodeling, as well as pathological processes including inflammation, arthritis, cardiovascular diseases, pulmonary diseases, and tumor invasion. Macrophage Metalloelastase, also known as Matrix metalloproteinase-12, Macrophage elastase, MMP12, and MMP-12, is a secreted protein that belongs to the peptidase M1A family. MMP12 is a macrophage-secreted elastase that is highly induced in the liver and lung in response to S. mansoni eggs and contains four hemopexin-like domains. MMP12 is a proteolytic enzyme responsible for the cleavage of plasminogen to angiotensin, which has an angiostatic effect. It may be involved in tissue injury and remodeling and has significant elastolytic activity. It may be related to prognosis in breast cancer patients. MMP12 promotes fibrosis by limiting the expression of specific ECM-degrading MMPs. Like MMP12, MMP13 expression is highly dependent on IL-13 and type I I-IL-4 receptor signaling. MMP12 is a potent proinflammatory and oncogenic molecule. MMP12 up-regulation plays a critical role in emphysema to lung cancer transition that is facilitated by inflammation.
存储条件Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
关键字MMP12 | MMP 12
MMP-12;MME;ME;matrix metallopeptidase 12;HME;TargetMol

公司简介


成立日期 (14年)
注册资本 589.8595万人民币
员工人数 100-500人
年营业额 ￥ 1亿以上
经营模式 贸易,工厂,试剂,定制,服务
主营行业 天然产物,生物化工,化学试剂,生物技术服务

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