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网站主页 CATHEPSIN C, HUMAN, 重组蛋白 (HIS) Cathepsin C, Human, 重组蛋白 (His)
  • Cathepsin C, Human, 重组蛋白 (His)|TMPY-00732|TargetMol

Cathepsin C, Human, 重组蛋白 (His)|TMPY-00732|TargetMol

Cathepsin C Protein, Human, Recombinant (His)
1130 10μg 起订
上海 更新日期:2026-05-08

TargetMol 中国(陶术生物)

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产品详情:

中文名称:
Cathepsin C, Human, 重组蛋白 (His)
英文名称:
Cathepsin C Protein, Human, Recombinant (His)
品牌:
TargetMol
产地:
美国
保存条件:
Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
产品类别:
抑制剂
种属:
Human
表达系统:
HEK293 Cells
蛋白长度:
A DNA sequence encoding the pro form of human cathepsin C (NP_001805.3) (Met 1-Leu 463) was expressed with a polyhistidine tag at the C-terminus. Predicted N terminal: Asp 25
标签:
C-His
货号:
T011|TMPY-00732

Product Introduction

Bioactivity

名称Cathepsin C Protein, Human, Recombinant (His)
描述Cathepsins are proteases found in many types of cells conserved in all animals, which have a vital role in mammalian cellular turnover such as bone resorption. The lysosomal cysteine protease Cathepsin C (CTSC), also known as dipeptidyl peptidase I (DPPI/DPP1), activates a number of granule-associated serine proteases with pro-inflammatory and immune functions by removal of their inhibitory N-terminal dipeptides. This lysosomal exo-cysteine protease belonging to the peptidase C1 family. Active cathepsin C is found in lysosomes as a 200-kDa multimeric enzyme. Subunits constituting this assembly all arise from the proteolytic cleavage of a single precursor giving rise to three peptides: the propeptide, the alpha- and the beta-chains. It is a central coordinator for activation of many serine proteases in immune/inflammatory cells. Defects in the Cathepsin C have been shown to be a cause of Papillon-Lefevre disease, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. Cathepsin C plays a key role in the activation of several degradative enzymes linked to tissue destruction in inflammatory diseases. Thus, it is a therapeutic target for the treatment of a number of inflammatory and autoimmune diseases.
存储条件Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
关键字PDON-1 | PDON 1 | DPP-1 | DPP 1
PLS;PDON1;PALS;JPD;JP;HMS;DPP-I;DPPI;DPP1;CPPI;cathepsin C;TargetMol

公司简介


成立日期 (14年)
注册资本 589.8595万人民币
员工人数 100-500人
年营业额 ¥ 1亿以上
经营模式 贸易,工厂,试剂,定制,服务
主营行业 天然产物,生物化工,化学试剂,生物技术服务

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