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网站主页 IL-15RA&IL-15, HUMAN, 重组蛋白 - PBS LYOPHILIZED (HFC) IL-15RA&IL-15, Human, 重组蛋白 - PBS Lyophilized (hFc)
  • IL-15RA&IL-15, Human, 重组蛋白 - PBS Lyophilized (hFc)|TMPJ-01462|TargetMol

IL-15RA&IL-15, Human, 重组蛋白 - PBS Lyophilized (hFc)|TMPJ-01462|TargetMol

IL-15RA & IL-15 Protein, Human, Recombinant - PBS Lyophilized (hFc)
￥1320 20μg 起订
上海 更新日期：2026-05-08

TargetMol 中国（陶术生物）

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联系人：邵经理
电话：400-821-0310拨打
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邮箱：xuexiang.shao@tsbiochem.com

产品详情:

中文名称：
IL-15RA&IL-15, Human, 重组蛋白 - PBS Lyophilized (hFc)
英文名称：
IL-15RA & IL-15 Protein, Human, Recombinant - PBS Lyophilized (hFc)
品牌：
TargetMol
产地：
美国
保存条件：
Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
纯度规格：
98.00%
产品类别：
抑制剂
种属：
Human
表达系统：
HEK293 Cells
蛋白长度：
Ile31-Asp96&Asn49-Ser162 (Asn120Asp)
标签：
C-hFc
货号：
T011|TMPJ-01462

Product Introduction

Bioactivity

名称IL-15RA & IL-15 Protein, Human, Recombinant - PBS Lyophilized (hFc)
描述IL15RA is a high-affinity receptor for interleukin-15. Il15ra associates as a heterotrimer with the IL-2 receptor beta and gamma subunits to initiate signal transduction. It can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Il15ra is expressed in special cells including a wide variety of Tand B cells and non-lymphoid cells.IL-15 is a cytokine that regulates T cell and natural killer cell activation and proliferation. IL-15 binds to the alpha subunit of the IL-15RA with high affinity. IL-15 also binds to the beta and gamma chains of the IL-2 receptor, but not the alpha subunit of the IL2 receptor. IL-15 is structurally and functionally related to IL-2. Both cytokines share some subunits of receptors, allowing them to compete for and negatively regulate each other's activity. The number of CD8+ memory T cells is controlled by a balance between IL-15 and IL-2. Despite their many overlapping functional properties, IL-2 and IL-15 are, in fact, quite distinct players in the immune system. IL-15 is constitutively expressed by a wide variety of cell types and tissues, including monocytes, macrophages and DCs. The enhanced activity of the IL-15N72D:IL-15RαSu/Fc complex is likely the result of the increased binding activity of IL-15N72D to IL-15Rβγ c , optimized cytokine trans-presentation by the IL-15RαSu domain, the dimeric nature of the cytokine domain and its increased in vivo half-life compared to IL-15. These findings indicate that this IL-15 superagonist complex could serve as a superior immunostimulatory therapeutic agent.
存储条件Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
关键字IL-15 Receptor a & IL-15 Fusion Protein | IL 15
Interleukin-15;IL15RA&IL15 Complex;IL15RA&IL15;IL-15 Receptor α & IL-15 Fusion Protein;IL-15 Receptor alpha & IL-15 Fusion Protein;IL-15;IL15;TargetMol

公司简介


成立日期 (14年)
注册资本 589.8595万人民币
员工人数 100-500人
年营业额 ￥ 1亿以上
经营模式 贸易,工厂,试剂,定制,服务
主营行业 天然产物,生物化工,化学试剂,生物技术服务

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