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网站主页 BCL2, HUMAN, 重组蛋白 (HIS) BCL2, Human, 重组蛋白 (His)
  • BCL2, Human, 重组蛋白 (His)|TMPY-02700|TargetMol

BCL2, Human, 重组蛋白 (His)|TMPY-02700|TargetMol

BCL2 Protein, Human, Recombinant (His)
2260 50μg 起订
上海 更新日期:2026-05-08

TargetMol 中国(陶术生物)

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联系人:邵经理
电话:400-821-0310拨打
手机:15002144251 拨打
邮箱:xuexiang.shao@tsbiochem.com

产品详情:

中文名称:
BCL2, Human, 重组蛋白 (His)
英文名称:
BCL2 Protein, Human, Recombinant (His)
品牌:
TargetMol
产地:
美国
保存条件:
Store at low temperature Store at -80°C
纯度规格:
96.00%
产品类别:
抑制剂
种属:
Human
表达系统:
E. coli
蛋白长度:
A DNA sequence encoding the human BCL2 isoform 1 (P10415-1) (Met 1-Asp 211) was expressed, with a polyhistide tag at the C-terminus. Predicted N terminal: Met 1
标签:
C-His
货号:
T011|TMPY-02700

Product Introduction

Bioactivity

名称BCL2 Protein, Human, Recombinant (His)
描述BCL2 (B-cell leukemia/lymphoma 2, N-Histidine-tagged), also known as Bcl-2, belongs to the Bcl-2 family. Bcl-2 family proteins regulate and contribute to programmed cell death or apoptosis. It is a large protein family and all members contain at least one of four BH (bcl-2 homology) domains. Certain members such as Bcl-2, Bcl-xl and Mcl1 are anti-apoptotic, whilst others are pro-apoptotic. Most Bcl-2 family members contain a C-terminal transmembrane domain that functions to target these proteins to the outer mitochondrial and other intracellular membranes. It is expressed in a variety of tissues. BCL2 blocks the apoptotic death of some cells such as lymphocytes. It also regulates cell death by controlling the mitochondrial membrane permeability and inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
存储条件Store at low temperature Store at -80°C
PPP1R50;Bcl-2;B-cell CLL/lymphoma 2;TargetMol

公司简介


成立日期 (14年)
注册资本 589.8595万人民币
员工人数 100-500人
年营业额 ¥ 1亿以上
经营模式 贸易,工厂,试剂,定制,服务
主营行业 天然产物,生物化工,化学试剂,生物技术服务

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