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网站主页 UBIQUITIN ACTIVATING ENZYME E1/UBA1, HUMAN, 重组蛋白 (HIS & GST) Ubiquitin Activating Enzyme E1/UBA1, Human, 重组蛋白 (His & GST)
  • Ubiquitin Activating Enzyme E1/UBA1, Human, 重组蛋白 (His & GST)|TMPY-02840|TargetMol

Ubiquitin Activating Enzyme E1/UBA1, Human, 重组蛋白 (His & GST)|TMPY-02840|TargetMol

Ubiquitin Activating Enzyme E1/UBA1 Protein, Human, Recombinant (His & GST)
773 10μg 起订
上海 更新日期:2026-05-08

TargetMol 中国(陶术生物)

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产品详情:

中文名称:
Ubiquitin Activating Enzyme E1/UBA1, Human, 重组蛋白 (His & GST)
英文名称:
Ubiquitin Activating Enzyme E1/UBA1 Protein, Human, Recombinant (His & GST)
品牌:
TargetMol
产地:
美国
保存条件:
Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
产品类别:
抑制剂
货号:
TMPY-02840

Product Introduction

Bioactivity

名称Ubiquitin Activating Enzyme E1/UBA1 Protein, Human, Recombinant (His & GST)
描述UBE1, also known as UBA1, belongs to the ubiquitin-activating E1 family. UBE1 gene complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cluster on chromosome Xp11.23. UBE1 catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. It also catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP. Defects in UBA1 can cause spinal muscular atrophy X-linked type 2 (SMAX2), also known as X-linked lethal infantile spinal muscular atrophy, distal X-linked arthrogryposis multiplex congenita or X-linked arthrogryposis type 1 (AMCX1). Spinal muscular atrophy refers to a group of neuromuscular disorders characterized by degeneration of the anterior horn cells of the spinal cord, leading to symmetrical muscle weakness and atrophy. SMAX2 is a lethal infantile form presenting with hypotonia, areflexia, and multiple congenital contractures.
存储条件Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
关键字UBE-1 | UBE 1 | SMAX-2 | SMAX 2 | POC-20 | POC 20 | GXP-1 | GXP 1 | CFAP-124 | CFAP 124 | AMCX-1 | AMCX 1
br
ubiquitin-like modifier activating enzyme 1|||UBE1X|||UBE1|||UBA1A|||SMAX2|||POC20|||GXP1|||CTD-2522E6.1|||CFAP124|||AMCX1|||A1ST|||A1S9T|||A1S9|TargetMol

公司简介


成立日期 (14年)
注册资本 589.8595万人民币
员工人数 100-500人
年营业额 ¥ 1亿以上
经营模式 贸易,工厂,试剂,定制,服务
主营行业 天然产物,生物化工,化学试剂,生物技术服务

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